Effectiveness of Cognitive Behavior Therapy for Persons With Depression

A Randomized Controlled Trial of the Effectiveness of Cognitive Behavior Therapy for Major Depression in Bangladesh

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05724680

Enrollment

148

Registered

2023-02-13

Start date

2018-08-10

Completion date

2019-05-30

Last updated

2023-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Brief summary

This was a randomized controlled clinical trial (RCT) carried out in three different hospitals in Dhaka city, Bangladesh.

Detailed description

This was a randomized controlled trial, conducted to determine the effectiveness of CBT for depression delivered by trained therapists with an adapted Bengali CBT (BaCBT) manual, as compared to a control group. The main objective of the current study was to examine the efficacy of CBT for persons with major depression in Bangladesh.

Interventions

OTHERcognitive behavior therapy

Psycho-therapeutic intervention

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Diagnosed with Major Depression * Must be able to take therapeutic session

Exclusion criteria

* active suicidal ideation * a co-morbid serious health condition * with psychotic features * currently on medication for depression * with an intellectual disability

Design outcomes

Primary

Measure	Time frame	Description
Change in Depression Scale	change from baseline to day 42, a separate outcome from day 42 to day 72	Depression Scale to measure depression. The total scale scores range from 30 to 150. Higher scores mean worse outcomes.

Secondary

Measure	Time frame	Description
Change in Anxiety Scale	change from baseline to day 42, a separate outcome from day 42 to day 72	Anxiety Scale, the possible range of scores from 0 to 144 and Higher scores mean worse outcomes.
Change in General Health Questionnaire-28	change from baseline to day 42, a separate outcome from day 42 to day 72	General Health Questionnaire-28, range of scores from 0 to 84, and Higher scores mean worse outcomes.
Change in Beck Scale for Suicidal Ideation	change from baseline to day 42, a separate outcome from day 42 to day 72	Beck Scale for Suicidal Ideation, range of scores from 0 to 42, and Higher scores mean worse outcomes.

Countries

Bangladesh

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026