Mitral Valve Disease
Conditions
Brief summary
Degenerative mitral regurgitation (MR) due to prolapse of the posterior leaflet is the most common dysfunction of the mitral valve (MV) in the Western world and is nowadays treated with a variety of surgical techniques. Quadrangular resection combined with annular plication and annuloplasty, as originally described by Carpentier, has been the standard approach for many years, before sliding/folding plasty and artificial chordae gained larger popularity.However, very few studies have been published on thevery long-term results (up to 20 years) of quadrangular resection and annular plication, often reporting only freedom from reoperation rather than from recurrent MR. This study aims to evaluate the very long-term (20 years) clinical and echocardiographic results of this approach, which was used for many years at the beginning of our mitral repair program.
Interventions
PROCEDUREQuadrangular resection and annular plication
Mitral regurgitation is treated removing the redundant tissue of the posterior leaflet, which is then reconstructed by sutures and plicating the posterior annulus
Sponsors
Michele De Bonis
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients * Affected by mitral valve posterior leaflet prolapse/flail causing severe mitral regurgitation * Treated with quadrangular resection of the posterior leaflet and annulus plication
Exclusion criteria
* Other patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality | Up to 20 years |
Countries
Italy
Outcome results
None listed