Deprescribing and Health-related Effects

Effective Deprescribing in Primary Care Without Deterioration of Health-related Outcomes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05721534

Enrollment

Registered

2023-02-10

Start date

2020-01-01

Completion date

2022-12-31

Last updated

2023-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Disease

Keywords

Primary care, Medication review, Deprescribing, Polypharmacy, Chronic disease management

Brief summary

In a primary care settled quality improvement project aiming to deprescribe medication through a medication review intervention, we investigated how the implemented medication changes affected health-related outcomes in real-life patients.

Detailed description

The project was approved by the Management in the Municipality of Frederikshavn. According to Danish legislation, no formal permission from the national or regional Committee on Health Research Ethics was required for this type of study, as patients were not treated inferior to usual care and no biological material was collected. It was conducted as a quality improvement project and informed consent was not required for the specific data collected. The study is in compliance with the General Data Protection Regulation and a part of North Denmark Region's record of processing activities (K2023-008).

Interventions

OTHERMedication review

Annual consultation focusing on pharmacological treatment. This specific consultation constituted the intervention. It included a structured review of the patient's health state, in addition to a structured medication review with a focus on appropriate medication and deprescribing.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 105 Years

Inclusion criteria

* new residents and residents that had not yet attended a consultation focusing on pharmacological treatment in The Chronic Care Model. * patients were invited for the consultation focusing on pharmacological treatment in the month of their birthday and, thereby, included randomly and consecutively throughout the study period.

Exclusion criteria

* unable to collaborate on follow-up questionnaires

Design outcomes

Primary

Measure	Time frame	Description
self-reported health status	4 months	(on a scale from 1 to 10)

Secondary

Measure	Time frame	Description
general condition	4 months	(rated on a 5-point Likert Scale)
functional level	4 months	rated on a 5-point Likert Scale

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026