Effects of Different Ventilatory Strategy on Intraoperative Atelectasis During Bronchoscopy Under General Anesthesia.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05720845

Enrollment

Registered

2023-02-09

Start date

2023-02-08

Completion date

2025-03-18

Last updated

2023-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Disorder

Keywords

atelectasis, general anesthesia

Brief summary

This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing interventional pulmonology procedures under general anesthesia. Ventilatory strategy to prevent reduce the intra-procedural development of atelectasis during interventional pulmonology procedures under general anesthesia.

Interventions

PROCEDUREVESPA

Using Ventilatory strategy of prevent atelectasis for General Anesthesia.

PROCEDUREconventional mechanical ventilation

Conventional mechanical ventilation for General Anesthesia.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Adult patients undergoing interventional pulmonology procedures with radial probe endobronchial ultrasound (RP-EBUS) for peripheral lung lesions * Recent (\< 4 weeks) chest computed tomography (CT) performed prior to the bronchoscopy

Exclusion criteria

* Patients with baseline lung consolidation, interstitial changes or lung masses (\> 3 cm in diameter) in dependent areas of the lung (right/left \[R/L\] B6, 9, or 10 bronchial segments) as seen on most recent CT * History of primary or secondary spontaneous pneumothorax

Design outcomes

Primary

Measure	Time frame	Description
Presence or absence of new atelectasis for each segment	During bronchoscopy, an average of 1 hour.	The proportion of patients identified as developing intraprocedural atelectasis by radial probe endobronchial ultrasound (RP-EBUS)

Secondary

Measure	Time frame
Ventilation-induced complications	Within 48 hours of bronchoscopy
Bronchoscopy-induced complications	Within 48 hours of bronchoscopy
Assess the regional ventilation distribution by Electrical impedance tomography (EIT)	During bronchoscopy, an average of 1 hour.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026