Esophageal Cancer, Postoperative Acute Myocardial Infarction, Postoperative Infection of Incision, Postoperative Pneumonia, Postoperative Pneumothorax, Postoperative Pulmonary Atelectasis
Conditions
Keywords
esophageal cancer, anesthesia, high flow nasal cannula, pneumonia, esophagectomy, acute myocardial infarction
Brief summary
This study will compare the effect of HFNC versus standard oxygen administration after elective esophagectomy for cancer.
Interventions
DEVICEAIRVO2
APPLICATION OF HIGH FLOW NASAL CANNULA OXYGEN FOR 48 HOURS AFTER ESOPHAGECTOMY
OTHERSTANDARD CARE
APPLICATION OF OXYGEN THROUGH STANDARD CARE FOR 48 HOURS AFTER ESOPHAGECTOMY
Sponsors
Cristian Deana
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* elective esophagectomy for cancer * METS≥4 * AGE 18-85 * Written informed consent
Exclusion criteria
* ASA\>3 * COPD≥ III stage according to GOLD criteria * FEV1\<50% * EF\<30% * NYHA\>2 * BMI\<17 or \>35 Kg/m2 * CKD with eGFR\<60 mL/min
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| POST-OPERATIVE PULMONARY COMPLICATIONS | within 30 days after surgery | Describe the frequency of PPC that include: pneumonia, pleural effusion, pneumothorax, atelectasis, ARDS, aspiration pneumonia, trachea-bronchial lesion, air leak |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| CARDIO-VASCULAR COMPLICATIONS | within 30 days after surgery | Describe the frequency of myocardial infarction, pulmonary edema, cardiac arrest, pulmonary embolism, deep venous thrombosis, stroke, pericardtis |
Countries
Italy
Contacts
Primary ContactCRISTIAN DEANA, MD
Outcome results
None listed