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Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults

Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults: a Single-Blind, Randomized Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05717452
Enrollment
80
Registered
2023-02-08
Start date
2023-02-01
Completion date
2023-04-30
Last updated
2023-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Affect, Executive Function, Mood

Keywords

Blueberry, Anthocyanins

Brief summary

This study aims to investigate whether consuming a drink containing powdered blueberries (equivalent to 150 g of fresh fruit) can improve mood and executive function in healthy emerging adults.

Detailed description

The present study will examine the psychological effects of a single dose of freeze-dried wild blueberries using a randomized, single-blind, placebo-controlled design. A total of 80 participants will be randomly allocated to consume either a drink prepared with 22 g blueberry powder or a drink prepared with 22 g placebo powder matched for macronutrients, flavour and colour.

Interventions

DIETARY_SUPPLEMENTBlueberry drink

22 g freeze-dried wild blueberry (Vaccinium angustifolium) powder mixed with 250 ml water.

DIETARY_SUPPLEMENTPlacebo drink

22 g placebo powder matched for macronutrients, color, and flavor mixed with 250 ml water.

Sponsors

Wild Blueberry Association of North America
CollaboratorOTHER
University of Reading
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)

Intervention model description

Standard two-arm trial with a placebo arm and active intervention arm

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* 18 to 25 years of age

Exclusion criteria

* Any medically significant condition or mental health disorder (e.g. diabetes, endocrine or gastrointestinal disorders) * Taking medication (excluding hormonal contraception or medication for asthma/seasonal allergies) * Allergy to blueberries or any other Vaccinium species

Design outcomes

Primary

MeasureTime frameDescription
Positive affect as measured by PANAS-X1.5 hours post-ingestionPositive affect will be calculated by adding the values of the 21 positive items of the Positive and Negative Affect Schedule-X and the additional item motivated. Thus, the scale will range from 0 to 88 points with higher scores indicating better mood.

Secondary

MeasureTime frameDescription
Reaction time1.5 hours post-ingestionThe average reaction time on correct trials of the task-switching test (in milliseconds).
Negative affect as measured by PANAS-X1.5 hours post-ingestionNegative affect will be calculated by adding the values of the 25 negative items of the Positive and Negative Affect Schedule-X. Thus, the scale will range from 0 to 100 points with higher scores indicating worse mood.
Executive function (accuracy)1.5 hours post-ingestionA task-switching test will be used to assess cognitive flexibility when switching between two predictable tasks requiring simple numerical decisions. The main outcome of interest is the average accuracy (0 to 100%).

Countries

United Kingdom

Contacts

Primary ContactClaire Williams, Professor
claire.williams@reading.ac.uk+441183787540

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026