Cervical Disc Disease, Cervical Disc Herniation, Cervical Stenosis
Conditions
Keywords
Cerebral blood oxygenation, Near infrared spectroscopy, Cervical disc disease, Cervical microsurgery
Brief summary
In anterior cervical disc surgery, head and neck extansion position and, surgical retraction used while reaching the anterior surface of the cervical vertebra can be affect the carotid blood flow and constituting a risk for cerebral ischaemia. In this study, we planned to investigate the relationship between head position and retraction, cerebral oxygenation and postoperative cognitive functions in patients undergoing anterior cervical disc surgery.
Interventions
DEVICENear infrared spectroscopy
The Near Infrared Spectroscopy (NIRS) is the method used for monitorize the risk of the development of cerebral ischaemia while providing information about brain tissue oxygenation.
Sponsors
Samsun University
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Aged 18-70 years * Preoperative Mini-Mental State Examination score of 27-30 * Who were planned to undergo anterior cervical disc surgery under general anesthesia
Exclusion criteria
* Patients with hypertension, severe pulmonary disease, anaemia, cardiac disease, ischaemic cerebrovascular disease, renal disease, hepatic disease, pregnancy, uncontrolled diabetes mellitus, stricture or obstruction in the carotid or vertebral arteries or * Body mass index (BMI) \>30.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Near-infrared spectroscopy (NIRS) | Intraoperative | Evaluate the effect of head position and surgical retraction on brain oxygenization with NIRS. Near-infrared spectroscopy (NIRS) is a brain imaging method that measures light absorbance to calculate oxy-hemoglobin (oxy-HB) and deoxy-hemoglobin (deoxy-HB), which provides an indirect measure of brain activity, particularly in the frontal cortex. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mini-Mental State Examination | 2 hours postoperative | Evaluate the effect of head position and surgical retraction on cognitive functions with using mini-mental state examination . A Mini-Mental State Examination (MMSE) is a set of 30 questions that commonly use to check for cognitive impairment (problems with thinking, communication, understanding and memory) |
Countries
Turkey (Türkiye)
Outcome results
None listed