Negative-Pressure Wound Therapy, Diabetic Foot
Conditions
Brief summary
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
Detailed description
Negative pressure wound therapy is a new noninvasive technique for treating open wounds. It works by removing fluid from the wound bed, reducing edema, and encouraging the growth and perfusion of new granulation tissue. Vacuum-Assisted Closure device (VAC) helps to remove fluid from open wounds through a sealed dressing and tubing which is connected to a collection container. Vacuum-assisted closure (VAC) can provide stable and persistent negative pressure, and there are several modes to choose from. VAC has played an important role in helping to close wounds, controlling infection, promoting angiogenesis, increasing blood flow, and promoting granulation tissue growth in wounds. It is now widely applied in all kinds of acute, chronic, and special wounds with good therapeutic results. However, there is a need to pay attention to contraindications and complications of VAC when it is used, avoiding secondary damage due to improper treatment.
Interventions
Patients Will Receive negative pressure wound therapy dressings before skin grafting to prepare the wound bed and after skin grafting.
OTHEROrdinary dressings with antibiotic ointment and gauze
Patients will Receive once daily dressing with antibiotic ointment and gauze before and after skin grafting.
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Patients will randomly be divided into two groups - study group and control group. Study group (A): Will Receive negative pressure wound therapy dressings before skin grafting to prepare the wound bed and after skin grafting. Control group (B): Will Receive once daily dressing with antibiotic ointment and gauze before and after skin grafting.
Eligibility
Sex/Gender
ALL
Age
20 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age group 20-75 years. * Patients with diabetic foot wounds who are scheduled for skin grafting.
Exclusion criteria
* Age \<20 years or \> 75 years. * An obvious septicemia. * Foot osteomyelitis. * Ulcer resulting from venous insufficiency. * Features of malignant ulcer. * Patients being treated with corticosteroids, immunosuppressive drugs. * Any other serious pre-existing cardiovascular, pulmonary or immunological disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Period of hospitalization. | 2 weeks | Number of days of patient hospitalization before and after grafting |
| Time of complete healing | 1 month | Number of days needed for each patient for complete healing after operation |
| Functional outcome | 5 months | Number of patients with full range of mobility at site of graft Vs number of patients with limited mobility |
| Patient satisfaction of aesthetic outcome | 5 months | Number of patients satisfied with the aesthetic result of the operation on a scale of 0-10 |
Countries
Egypt
Contacts
Primary ContactHady K Elhossiny, Resident
Backup ContactGamal Y Elsayed, Professor
Outcome results
None listed