Bowel Dysfunction
Conditions
Keywords
anorectal malformation, Bowel function, risk factors
Brief summary
The present study was designed to evaluate bowel function in preschool and early childhood in a large number of patients with anorectal Malformation and to identify the associated risk factors for bowel dysfunction.
Detailed description
Anorectal malformation (ARM) is a type of congenital malformation resulting from post-embryonic intestinal dysgenesis, occurring in about 1 in 5000 cases.Surgery is an effective means of treating ARM,which includes reconstruction of the anus and treatment of associated deformities. However, even with reconstruction of the anus, most children still have serious complications, such as constipation, fecal incontinence, urinary incontinence, and sexual dysfunction, in the mid-to-long postoperative period.A lot of studies have been designed to explore the trend toward normal bowel habits from preschool and early childhood age to adolescence or adult; however, no apparent improvement in bowel habits was completely confirmed. In contrast, many reports have shown that poor bowel function in preschool and early childhood may lead to social problems and depression in adolescence and adult.The reasons for bowel dysfunction of ARM in preschool and early childhood were complicated and undefined,including associated malformations, the type of ARM, and the development of the perianal sphincter,etc.The bowel function score (BFS) is currently used to assess mid- and long-term anal function in patients with ARM, and comprises seven major categories (e.g., self-perception, fecal control, stool collection, and social problems) with a total of 20 points, or less than 17 points, for the presence of anal weakness (11-17 points, for the general weakness, or less than 11 points, for the severe weakness) .Therefore,bowel function at preschool and early childhood should be evaluated in a large number of patients with ARM and the associated risk factors for bowel dysfunction should also be assessed. The present study was designed to evaluate bowel function in preschool and early childhood in a large number of patients with ARM and to identify the associated risk factors for bowel dysfunction using BFS.
Interventions
OTHERbowel function score questionnaire survey
Bowel function score(BFS, total 20 points) was approved by Rintala in 1995, and patients with a score ≥ 17 were considered to have normal bowel habits. 7 items were in BFS, including the ability to hold back defecation, feeling/reporting the urge to defecate, frequency of defecation, soiling, accidents, constipation. In December 2022, BFS questionnaire surveys were conducted on children with ARM who underwent surgical repair between January 2017 and December 2019 at Children's Hospital of Nanjing Medical University.
Sponsors
Nanjing Children's Hospital
Study design
Observational model
CASE_CROSSOVER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
4 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Anorectal malformation \>4 years old
Exclusion criteria
Down syndrome patients \<4 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bowel function score in partipants with ARM | through study completion, an average of 6 year | approved by Rintala in 1995, and patients with a score ≥ 17 were considered to have normal bowel habits |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sacral ratio in partipants with ARM | through study completion, an average of 6 year | test by X ray |
Other
| Measure | Time frame | Description |
|---|---|---|
| Number of partipants performed with every surgical method | through study completion, an average of 6 year | Posterior sagittal approach to anoplasty or Anterior sagittal approach to anoplasty or Laparoscopic assisted anoplasty |
| Number of partipants with every type of ARM | through study completion, an average of 6 year | confirmed in surgery |
| Number of partipants with reoperation | through study completion, an average of 6 year | re-anoplasty |
| Number of partipants with abnormal spinal cord | through study completion, an average of 6 year | tethered cord or other |
| age at surgery of partipants with ARM | through study completion, an average of 6 year | age at surger |
Countries
China
Contacts
Primary ContactChanggui Lu, Dr
Outcome results
None listed