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Weight Discrimination and Poor Cardiovascular Health

Mechanisms Explaining the Link Between Weight Discrimination and Poor Cardiovascular Health

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05714696
Enrollment
333
Registered
2023-02-06
Start date
2023-02-05
Completion date
2024-04-26
Last updated
2025-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Brief summary

People with obesity regularly experience discrimination on the basis of their body weight and such experiences are associated with increased risk for poor cardiovascular health. The goal of this clinical trial is to identify cognitive, affective, behavioral, and physiological factors that explain the relationship between weight discrimination and poor health outcomes. A diverse sample of adults with obesity will be randomly assigned to a social interaction encounter that simulates a typical weight discrimination experience (experimental manipulation) vs. a control manipulation that does not involve discrimination. The investigators will examine the immediate effects of the experimental manipulation on cognitive (e.g., self-regulation), affective (e.g., negative emotion), behavioral (e.g., comfort eating), and physiological (e.g., cortisol secretion) outcomes. Two additional aims of the study are to identify psychological traits that moderate responses to weight discrimination and to assess whether the negative health effects of weight discrimination differ by age, sex/gender, race, or ethnicity.

Detailed description

Discrimination is a critical social determinant of health that underlies poor health outcomes. One common but understudied form of discrimination is weight discrimination. Weight discrimination is the behavioral manifestation of weight stigma-the social devaluation of people with excess body weight. Findings suggest that the stress produced by weight discrimination prompts weight gain, creating a vicious cycle between weight discrimination and obesity. Further, there is now well-documented evidence that experiencing weight discrimination is associated with increased risk for cardiovascular disease. Little is known, however, about mechanisms explaining the link between weight discrimination and poor cardiovascular health. Using a rigorous experimental approach, this project will identify mechanisms through which weight discrimination harms health. Findings will facilitate the long-term goal of this research: interventions to decrease the negative health consequences of weight discrimination. As a step toward this goal, this project proposes to conduct an experiment in which a diverse sample of adults with obesity will be randomly assigned to experience (vs. not experience) weight discrimination in a controlled experimental setting. Drawing on previous research and the investigators' pilot data, the interpersonal context chosen for the study simulates situations in which people with obesity commonly experience weight discrimination in their daily lives (e.g., employment settings). The study will involve two parts: a pre-session baseline survey and an experimental session that will take place in the lab. The baseline survey will be completed online and will assess individual difference variables/psychological variables and demographic characteristics. The in-person lab visit will take place on campus about one week after completion of the baseline survey. The study manipulation (i.e., intervention) will be delivered during the lab visit. Primary outcome variables will be assessed during the lab visit, after delivery of the intervention. The following aims will be tested: (1) Identify early-stage cognitive, affective, behavioral, and physiological mechanisms activated by experimentally manipulated weight discrimination; (2) Identify psychological variables (e.g., internalized weight bias) that moderate effects of weight discrimination; and (3) Identify demographic characteristics (e.g., gender, race) that moderate effects of weight discrimination. Exposure to weight discrimination (vs. control) is hypothesized to result in elevated responses on early-stage mechanisms that culminate in poor cardiovascular health (e.g., impaired self-regulation, higher negative emotion, more social withdrawal and comfort eating, increased cortisol secretion). This research will identify novel and highly modifiable targets for interventions designed to reduce the negative health effects of weight discrimination. In testing moderator variables, this work will identify individuals who display vulnerability vs. resilience to the harmful effects of discrimination. Information about moderators will thus help future intervention efforts target those individuals most likely to benefit from intervention. Given the high prevalence of obesity and the millions of Americans affected by weight discrimination, this research will address a crucial public health issue.

Interventions

BEHAVIORALWeight discrimination experience

In the experimental condition, participants will learn that their group members are biased against overweight people but not elderly or racial/ethnic minority individuals, as indicated by the getting to know you summary ratings handout. Participants will also receive negative feedback about their personal attributes by being labeled with negative weight-based stereotypes. Although some ratings will be positive (e.g., they will receive high ratings on being friendly and kind), participants will be rated poorly on attributes viewed as necessary to develop a strong marketing campaign (i.e., motivation to work hard, possessing self-discipline to persist at the task, and competence). After (ostensibly) assembling the group's preferences, the experimenter will inform participants that no one selected them to be their partner, thus they will perform the next few tasks alone. This manipulation has been shown to prompt feelings of social exclusion.

BEHAVIORALControl experience

In the control condition, participants will learn that their group members have positive attitudes toward people with higher body weight, as well as elderly and racial/ethnic minority individuals, as indicated by the getting to know you summary ratings handout. Participants will also receive positive feedback about their personal attributes, as indicated by the summary ratings averaged across the three members. Finally, participants in the control condition will be told that one of their group members had to leave unexpectedly for a family emergency, so pairs cannot be assembled as usual, thus they will perform the next few tasks alone. This manipulation should not prompt feelings of social exclusion.

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)
CollaboratorNIH
Florida State University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* (1) body mass index (BMI) greater than or equal to 30 (units: weight in kilograms divided by height in meters squared; BMI criteria for obesity) * (2) 18 years of age or older * (3) able to read and understand English * (4) have Internet access (to complete the baseline survey) * (5) able to come to FSU's campus to take part in a lab-based study

Exclusion criteria

* (1) having participated in any of our pilot studies on weight stigma * (2) diagnosed with a current major psychiatric disorder (e.g., major depressive disorder, eating disorder) * (3) pregnant or nursing * (4) diagnosed with Cushing syndrome or taking steroid-based medications * (5) having allergies to ingredients in the foods being offered during the taste test (e.g., gluten, peanuts).

Design outcomes

Primary

MeasureTime frameDescription
Negative Affect2 minutes after delivery of the interventionA modified version of the Positive and Negative Affect Scale-Expanded Form (PANAS-X) will be used to assess emotions in response to the experimental manipulation. The scale demonstrates good validity and reliability. Emotions will be assessed with 46 adjectives (e.g., angry, confident) by indicating the extent to each emotion is felt at that moment (1=very slightly or not at all to 5=extremely). A composite score for negative affect will be created by taking the average of the relevant adjectives. Scores will range from 1 to 5, with higher scores indicating more negative emotion.
Positive Affect2 minutes after delivery of the interventionA modified version of the Positive and Negative Affect Scale-Expanded Form (PANAS-X) will be used to assess emotions in response to the experimental manipulation. The scale demonstrates good validity and reliability. Emotions will be assessed with 46 adjectives (e.g., angry, confident) by indicating the extent to each emotion is felt at that moment (1=very slightly or not at all to 5=extremely). A composite score for positive affect will be created by taking the average of the relevant adjectives. Scores will range from 1 to 5, with higher scores indicating more positive emotion.
Self-efficacy for Weight Control Behavior6 minutes after delivery of the interventionSelf-efficacy (perceived confidence) in one's ability to engage in weight control behaviors (e.g., dietary restraint, physical activity) over the next six months will be assessed. Self-efficacy for dietary restraint will be assessed with the short form of the Weight Efficacy Lifestyle Questionnaire (e.g., I can resist eating … when I am depressed or down; 8 items). Self-efficacy for physical activity will be assessed with the Exercise Self-efficacy Scale (e.g., I am confident I can participate in regular exercise when … I am tired; 5 items). Weight control items will be interspersed with items assessing self-efficacy for other health behaviors (e.g., flu vaccination, sleep). Each item will be rated on an 8-point scale (0=not at all confident to 7=very confident). Items will be averaged to create a composite score. Scores will range from 0 to 7, with higher scores indicating higher self-efficacy for weight control behavior.
Intentions for Weight Control Behavior10 minutes after delivery of the interventionUsing the same health behaviors assessed for self-efficacy, intentions for weight control behavior will be assessed (i.e., intentions to engage in each behavior over the next six months). Each item will be rated on an 8-point scale (0=strongly disagree to 7=strongly agree). Items will be averaged to create a composite score. Scores will range from 0 to 7, with higher scores indicating higher intentions to engage in weight control behavior.
Executive control_accuracy15 minutes after delivery of the interventionThe Stroop task provides a measure of executive control by assessing the ability to inhibit an automatic response (reading) in favor of performing a more controlled task (color naming). The task is a classic, widely used and well-validated measure of executive control. Eight blocks of 20 trials will be performed that will take approximately 5 minutes to complete. Executive control scores will be calculated for response accuracy and speed. Metric: accuracy (percentage of correct answers on mismatched trials). A lower percentage of correct answers on mismatched trials indicates worse executive control.
Executive control_speed15 minutes after delivery of the interventionThe Stroop task provides a measure of executive control by assessing the ability to inhibit an automatic response (reading) in favor of performing a more controlled task (color naming). The task is a classic, widely used and well-validated measure of executive control. Eight blocks of 20 trials will be performed that will take approximately 5 minutes to complete. Executive control scores will be calculated for accuracy and speed (reaction time). Metric: reaction time (average reaction time in milliseconds on mismatched trials). Longer reaction times on mismatched trials indicate worse executive control.
Delay Discounting20 minutes after delivery of the interventionDelay discounting involves the subjective depreciation of an incentive based on its timing. The measure assesses the ability to delay gratification, that is, a tendency to prioritize larger long-term rewards over smaller short-term rewards. The task involves choosing short vs. long-term rewards from a set of five dichotomous choices (e.g., to receive $1 immediately or $10 in one month). The task takes about 1 minute to administer, is highly reliable, and correlates well with longer and more extensive measures of delay discounting (metric: discount rate (k)). Scores will range from 0.000110 to 24, with higher scores indicating more impulsivity/lower ability to delay gratification.
Change in Cortisol From Baseline to First Follow-up Assessment25 minutes after delivery of the interventionThe investigators will measure cortisol secretion via saliva (passive drool) 25 minutes after delivery of the intervention (first follow-up) and compare it to baseline cortisol levels.
Comfort Eating30 minutes after delivery of the interventionComfort eating will be assessed via an eating task to objectively measure hyper-palatable (high-fat, -sodium, -sugar, and -carbohydrate) food intake. To avoid floor effects, the eating task will take place under the guise of a faux taste test, which will ostensibly guide the development of the food marketing campaign later during the study. To avoid ceiling effects and to allow eating behavior without fear that the experimenter will negatively judge the amount eaten, large quantities of each food will be made available. The task will take 10 minutes to complete and will be conducted in a private room. Bowls will be weighed (unobtrusively) before and after the task to compute the difference in grams, which will then be converted to kilocalories based on published nutrition information from the food maker. Higher kilocalorie consumption indicates a tendency to engage in more comfort eating during times of stress.
Social Withdrawal45 minutes after delivery of the interventionSocial withdrawal will be assessed with a measure from previous research. The experimenter will present three options for working on the final task: alone, with a former group member, or with a new partner. Choosing to work alone reflects a desire to avoid social interaction. Each response will be assigned a numerical code (work alone = 0; work with a former group member = 1; work with a new partner = 2). Scores of zero indicate a greater tendency to withdraw socially during times of stress.
Change in Cortisol From Baseline to Second Follow-up Assessment60 minutes after delivery of the interventionThe investigators will measure cortisol secretion via saliva (passive drool) 60 minutes after delivery of the intervention (second follow-up) and compare it to baseline cortisol levels.

Countries

United States

Participant flow

Recruitment details

Participants were recruited from the local community between February 2023 and April 2024. The first participant was enrolled on February 5, 2023 and the last participant was enrolled on April 26, 2024.

Pre-assignment details

Of 333 enrolled participants, 271 were randomized to experimental condition.

Participants by arm

ArmCount
Weight Discrimination Experience
Participants in the experimental condition will: 1. Learn that their group mates are biased against overweight people (i.e., they have negative attitudes toward people with higher body weight), 2. Receive feedback about their personal attributes that is consistent with negative weight-based stereotypes (e.g., lacking self-discipline), and 3. Not be selected as a partner for the remaining lab tasks (i.e., this experience may prompt feelings of social exclusion). Weight discrimination experience: In the experimental condition, participants will learn that their group members are biased against overweight people but not elderly or racial/ethnic minority individuals, as indicated by the getting to know you summary ratings handout. Participants will also receive negative feedback about their personal attributes by being labeled with negative weight-based stereotypes. Although some ratings will be positive (e.g., they will receive high ratings on being friendly and kind), participants will be rated poorly on attributes viewed as necessary to develop a strong marketing campaign (i.e., motivation to work hard, possessing self-discipline to persist at the task, and competence). After (ostensibly) assembling the group's preferences, the experimenter will inform participants that no one selected them to be their partner, thus they will perform the next few tasks alone. This manipulation has been shown to prompt feelings of social exclusion.
136
Control Experience
Participants in the control condition will: 1. Learn that their group mates are very accepting of overweight people (i.e., they have positive attitudes toward people with higher body weight), 2. Receive positive feedback about their personal attributes that is not consistent with negative weight-based stereotypes, and 3. Will be told that one of their group members had to leave early for an emergency so the pairs cannot be assembled as usual (i.e., this experience should not prompt feelings of social exclusion). Control experience: In the control condition, participants will learn that their group members have positive attitudes toward people with higher body weight, as well as elderly and racial/ethnic minority individuals, as indicated by the getting to know you summary ratings handout. Participants will also receive positive feedback about their personal attributes, as indicated by the summary ratings averaged across the three members. Finally, participants in the control condition will be told that one of their group members had to leave unexpectedly for a family emergency, so pairs cannot be assembled as usual, thus they will perform the next few tasks alone. This manipulation should not prompt feelings of social exclusion.
135
Total271

Baseline characteristics

CharacteristicWeight Discrimination ExperienceControl ExperienceTotal
Age, Continuous37.99 years
STANDARD_DEVIATION 13.41
38.70 years
STANDARD_DEVIATION 13.28
38.34 years
STANDARD_DEVIATION 13.33
Body mass index37.99 kg/m2
STANDARD_DEVIATION 6.99
37.22 kg/m2
STANDARD_DEVIATION 5.73
37.61 kg/m2
STANDARD_DEVIATION 6.39
Ethnicity (NIH/OMB)
Hispanic or Latino
16 Participants16 Participants32 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
120 Participants119 Participants239 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants1 Participants2 Participants
Race (NIH/OMB)
Asian
6 Participants2 Participants8 Participants
Race (NIH/OMB)
Black or African American
43 Participants41 Participants84 Participants
Race (NIH/OMB)
More than one race
5 Participants5 Participants10 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
1 Participants0 Participants1 Participants
Race (NIH/OMB)
Unknown or Not Reported
3 Participants1 Participants4 Participants
Race (NIH/OMB)
White
77 Participants85 Participants162 Participants
Region of Enrollment
United States
136 participants135 participants271 participants
Sex/Gender, Customized
Female
109 Participants108 Participants217 Participants
Sex/Gender, Customized
Male
26 Participants26 Participants52 Participants
Sex/Gender, Customized
Prefer not to answer
0 Participants1 Participants1 Participants
Sex/Gender, Customized
Unknown
1 Participants0 Participants1 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 1360 / 135
other
Total, other adverse events
0 / 1360 / 135
serious
Total, serious adverse events
0 / 1360 / 135

Outcome results

Primary

Change in Cortisol From Baseline to First Follow-up Assessment

The investigators will measure cortisol secretion via saliva (passive drool) 25 minutes after delivery of the intervention (first follow-up) and compare it to baseline cortisol levels.

Time frame: 25 minutes after delivery of the intervention

Population: There are some missing data on this variable due to poor quality saliva samples (too watery).

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceChange in Cortisol From Baseline to First Follow-up Assessment.0000 ug/dLStandard Deviation 0
Control ExperienceChange in Cortisol From Baseline to First Follow-up Assessment.0076 ug/dLStandard Deviation 0.0874
p-value: 0.311t-test, 2 sided
Primary

Change in Cortisol From Baseline to Second Follow-up Assessment

The investigators will measure cortisol secretion via saliva (passive drool) 60 minutes after delivery of the intervention (second follow-up) and compare it to baseline cortisol levels.

Time frame: 60 minutes after delivery of the intervention

Population: There are some missing data on this variable due to poor quality saliva samples (too watery). Of note, we were not able to run the statistical analysis on this variable due to the lack of variability in both groups.

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceChange in Cortisol From Baseline to Second Follow-up Assessment.0000 ug/dLStandard Deviation 0
Control ExperienceChange in Cortisol From Baseline to Second Follow-up Assessment.0000 ug/dLStandard Deviation 0
Primary

Comfort Eating

Comfort eating will be assessed via an eating task to objectively measure hyper-palatable (high-fat, -sodium, -sugar, and -carbohydrate) food intake. To avoid floor effects, the eating task will take place under the guise of a faux taste test, which will ostensibly guide the development of the food marketing campaign later during the study. To avoid ceiling effects and to allow eating behavior without fear that the experimenter will negatively judge the amount eaten, large quantities of each food will be made available. The task will take 10 minutes to complete and will be conducted in a private room. Bowls will be weighed (unobtrusively) before and after the task to compute the difference in grams, which will then be converted to kilocalories based on published nutrition information from the food maker. Higher kilocalorie consumption indicates a tendency to engage in more comfort eating during times of stress.

Time frame: 30 minutes after delivery of the intervention

Population: There are some missing data on this variable due to participant eating restrictions or allergies that prevented them completing the taste test as designed.

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceComfort Eating299.42 kcalsStandard Deviation 194.72
Control ExperienceComfort Eating365.73 kcalsStandard Deviation 173.83
p-value: 0.004t-test, 2 sided
Primary

Delay Discounting

Delay discounting involves the subjective depreciation of an incentive based on its timing. The measure assesses the ability to delay gratification, that is, a tendency to prioritize larger long-term rewards over smaller short-term rewards. The task involves choosing short vs. long-term rewards from a set of five dichotomous choices (e.g., to receive $1 immediately or $10 in one month). The task takes about 1 minute to administer, is highly reliable, and correlates well with longer and more extensive measures of delay discounting (metric: discount rate (k)). Scores will range from 0.000110 to 24, with higher scores indicating more impulsivity/lower ability to delay gratification.

Time frame: 20 minutes after delivery of the intervention

Population: There are some missing data on this variable due to experimenter error.

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceDelay Discounting0.86 score on a scaleStandard Deviation 3.87
Control ExperienceDelay Discounting1.20 score on a scaleStandard Deviation 4.78
p-value: 0.527t-test, 2 sided
Primary

Executive control_accuracy

The Stroop task provides a measure of executive control by assessing the ability to inhibit an automatic response (reading) in favor of performing a more controlled task (color naming). The task is a classic, widely used and well-validated measure of executive control. Eight blocks of 20 trials will be performed that will take approximately 5 minutes to complete. Executive control scores will be calculated for response accuracy and speed. Metric: accuracy (percentage of correct answers on mismatched trials). A lower percentage of correct answers on mismatched trials indicates worse executive control.

Time frame: 15 minutes after delivery of the intervention

Population: There are some missing data on this variable due to experimenter error.

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceExecutive control_accuracy96 percentage of correct responsesStandard Deviation 5
Control ExperienceExecutive control_accuracy96 percentage of correct responsesStandard Deviation 4.7
p-value: 0.442t-test, 2 sided
Primary

Executive control_speed

The Stroop task provides a measure of executive control by assessing the ability to inhibit an automatic response (reading) in favor of performing a more controlled task (color naming). The task is a classic, widely used and well-validated measure of executive control. Eight blocks of 20 trials will be performed that will take approximately 5 minutes to complete. Executive control scores will be calculated for accuracy and speed (reaction time). Metric: reaction time (average reaction time in milliseconds on mismatched trials). Longer reaction times on mismatched trials indicate worse executive control.

Time frame: 15 minutes after delivery of the intervention

Population: There are some missing data on this variable due to experimenter error.

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceExecutive control_speed1191 millisecondsStandard Deviation 429
Control ExperienceExecutive control_speed1362 millisecondsStandard Deviation 492
Primary

Intentions for Weight Control Behavior

Using the same health behaviors assessed for self-efficacy, intentions for weight control behavior will be assessed (i.e., intentions to engage in each behavior over the next six months). Each item will be rated on an 8-point scale (0=strongly disagree to 7=strongly agree). Items will be averaged to create a composite score. Scores will range from 0 to 7, with higher scores indicating higher intentions to engage in weight control behavior.

Time frame: 10 minutes after delivery of the intervention

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceIntentions for Weight Control Behavior4.91 score on a scaleStandard Deviation 1.3
Control ExperienceIntentions for Weight Control Behavior4.70 score on a scaleStandard Deviation 1.28
p-value: 0.163t-test, 2 sided
Primary

Negative Affect

A modified version of the Positive and Negative Affect Scale-Expanded Form (PANAS-X) will be used to assess emotions in response to the experimental manipulation. The scale demonstrates good validity and reliability. Emotions will be assessed with 46 adjectives (e.g., angry, confident) by indicating the extent to each emotion is felt at that moment (1=very slightly or not at all to 5=extremely). A composite score for negative affect will be created by taking the average of the relevant adjectives. Scores will range from 1 to 5, with higher scores indicating more negative emotion.

Time frame: 2 minutes after delivery of the intervention

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceNegative Affect1.43 score on a scaleStandard Deviation 0.49
Control ExperienceNegative Affect1.29 score on a scaleStandard Deviation 0.33
p-value: 0.007t-test, 2 sided
Primary

Positive Affect

A modified version of the Positive and Negative Affect Scale-Expanded Form (PANAS-X) will be used to assess emotions in response to the experimental manipulation. The scale demonstrates good validity and reliability. Emotions will be assessed with 46 adjectives (e.g., angry, confident) by indicating the extent to each emotion is felt at that moment (1=very slightly or not at all to 5=extremely). A composite score for positive affect will be created by taking the average of the relevant adjectives. Scores will range from 1 to 5, with higher scores indicating more positive emotion.

Time frame: 2 minutes after delivery of the intervention

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperiencePositive Affect2.83 score on a scaleStandard Deviation 0.94
Control ExperiencePositive Affect3.04 score on a scaleStandard Deviation 0.82
p-value: 0.049t-test, 2 sided
Primary

Self-efficacy for Weight Control Behavior

Self-efficacy (perceived confidence) in one's ability to engage in weight control behaviors (e.g., dietary restraint, physical activity) over the next six months will be assessed. Self-efficacy for dietary restraint will be assessed with the short form of the Weight Efficacy Lifestyle Questionnaire (e.g., I can resist eating … when I am depressed or down; 8 items). Self-efficacy for physical activity will be assessed with the Exercise Self-efficacy Scale (e.g., I am confident I can participate in regular exercise when … I am tired; 5 items). Weight control items will be interspersed with items assessing self-efficacy for other health behaviors (e.g., flu vaccination, sleep). Each item will be rated on an 8-point scale (0=not at all confident to 7=very confident). Items will be averaged to create a composite score. Scores will range from 0 to 7, with higher scores indicating higher self-efficacy for weight control behavior.

Time frame: 6 minutes after delivery of the intervention

ArmMeasureValue (MEAN)Dispersion
Weight Discrimination ExperienceSelf-efficacy for Weight Control Behavior4.29 score on a scaleStandard Deviation 1.42
Control ExperienceSelf-efficacy for Weight Control Behavior3.91 score on a scaleStandard Deviation 1.42
p-value: 0.029t-test, 2 sided
Primary

Social Withdrawal

Social withdrawal will be assessed with a measure from previous research. The experimenter will present three options for working on the final task: alone, with a former group member, or with a new partner. Choosing to work alone reflects a desire to avoid social interaction. Each response will be assigned a numerical code (work alone = 0; work with a former group member = 1; work with a new partner = 2). Scores of zero indicate a greater tendency to withdraw socially during times of stress.

Time frame: 45 minutes after delivery of the intervention

Population: One participant is missing data due to experimenter error.

ArmMeasureCategoryValue (COUNT_OF_PARTICIPANTS)
Weight Discrimination ExperienceSocial WithdrawalWork by self72 Participants
Weight Discrimination ExperienceSocial WithdrawalWork with former group member28 Participants
Weight Discrimination ExperienceSocial WithdrawalWork with new group member36 Participants
Control ExperienceSocial WithdrawalWork by self55 Participants
Control ExperienceSocial WithdrawalWork with former group member52 Participants
Control ExperienceSocial WithdrawalWork with new group member27 Participants
p-value: 0.005Chi-squared

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026