Meibomian Gland Dysfunction
Conditions
Brief summary
The study aims to determine the impact of Meibomian Gland Dysfunction (MGD) dry eye on low contrast black/white (luminance) and cone color sensitivity performance and improvement in these functions after in-house non-invasive Meibomian gland (MG) expression.
Detailed description
This study offers possible benefits from gland expression to patients and subjects in terms of clinical measurements and care associated with meibomian gland dysfunction impacting all age ranges. Prior studies show that these interventions improve dry eye symptoms with intent to improve vision, low contrast color, and B/W vision after intervention in this study.
Interventions
PROCEDUREMeibomian gland (MG) expression
The procedure is performed with a sterile cotton tip applicator once in the upper and lower eyelids of the subject's choosing.
Sponsors
University of the Incarnate Word
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Individuals over the age of 18 years * Healthy individuals with reported symptoms of dry eye such as burning, stinging, fluctuating vision, inappropriate tearing, and feelings of grittiness particularly with prolonged near work
Exclusion criteria
* Under the age of 18 * Individuals currently using prescription eye medications for dry eye / MGD / inflammation / Infections or any other treatments.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Response Time on Cone Contrast Test (CCT, Innova Systems, Inc.) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures average response time in seconds to see red, green and blue low contrast letters. |
| Change in Cone Contrast Sensitivity on the Cone Contrast Test (CCT, Innova Systems, Inc.) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures the lowest contrast (contrast sensitivity) to see red, green and blue cone specific letters. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Response Time on Black White Contrast Sensitivity Test (Innova Systems, Inc) Response Time | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures average response time in seconds to see low contrast black/white letters |
| Change in Visual Acuity Test at Low Contrast (Innova Systems, Inc) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures the smallest low contrast letters which can be seen. |
| Change in Sensitivity on Cone Contrast Color Naming test (CCNT) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures the lowest contrast (contrast sensitivity) to see red, green, blue and grey letters. |
| Change in Color Naming Accuracy on Cone Contrast Color Naming test (CCNT) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures the accuracy of naming (number correct) low contrast red, green, blue and grey letters. |
| Change in Response Time on Visual Acuity Test at Low Contrast (Innova Systems, Inc) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures average response time in seconds to see low contrast visual acuity letters |
| Change in Black White Contrast Sensitivity (Innova Systems, Inc) | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | This computer test measures the lowest contrast (contrast sensitivity) to see black/white letters. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in High Contrast Visual Acuity | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | The Precision Vision, Inc. Super Vision Chart will be used to measure visual acuity (smallest black letters on a white background that can be seen). |
| Change in Small Letter Contrast Sensitivity | This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention. | The Precision Vision, Inc. Super Vision Chart will be used to measure the lowest contrast (contrast sensitivity) which can be seen using small (20/25) letters. |
Countries
United States
Outcome results
None listed