Outcomes After PCI of the Aneurysmatic Right Coronary Artery

Percutaneous Coronary Interventions of the Aneurysmatic and Ectasic Right Coronary Artery in the Acute Setting: Management and Immediate- and Long-Term Outcomes The RIGHT-MARE Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05713201

Acronym

RIGHT-MARE

Enrollment

Registered

2023-02-06

Start date

2022-11-01

Completion date

2024-12-01

Last updated

2023-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Ectasia, Coronary Disease, Right Coronary Artery Occlusion, Right Coronary Artery Stenosis, STEMI

Keywords

PCI, Acute Coronary Syndrome, Aneurysmatic Right Coronary Artery

Brief summary

This study aims to evaluate procedural and clinical outcomes of acute coronay syndrome (ACS) patients with aneurysmatic culprit right coronary artery (RCA).

Detailed description

The investigators sought differences in procedural (slow-flow, no-reflow, distal embolisation,Thrombolysis in Myocardial Infarction final flow (TIMI) etc.) and in immediate and long-term clinical outcomes between several subgroups such as index vs staged percutaneous coronary intervention (PCI), premedication vs none, use of IIb/IIIa inhibitors vs none, bare metal stent (BMS) vs drug eluting stent (DES), ultrathin DES vs thick DES, durable polymer vs bioresorbable or free polymer etc. The investigators also want to investigate the efficacy of different technical manoeuvres involved in resolving high thrombotic burden before stent deployment, such as thrombus aspiration, dilatation, intracoronary infusion of adenosine or thrombolytic agents, direct stenting etc.). Long-term follow-up includes target vessel failure (Cardiac Death, target vessel MI, clinically-driven target vessel revascularisation), define or probable stent thrombosis, target vessel revascularisation for ACS, clinically driven target vessel revascularisation and intrastent restenosis.

Interventions

PROCEDUREPercutaneous Coronary Intervention

Treatment of coronary stenoses with a drug-eluting stent or balloon

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Patients with ACS of the aneurysmatic or ectasic RCA * Patient with at least 6 months clinical or angiographic follow-up * Patients with accurate procedural and clinical records (particularly use of drugs before, during and after procedure, according to RCA PCI procedure (index or staged).

Exclusion criteria

* Elective aneurysmatic or ectasic RCA PCI * Patient with lack of accurate procedural and clinical data * Patient with lack of clinical or angiographic follow up

Design outcomes

Primary

Measure	Time frame	Description
Technical success	Procedural (from the start to the end of the procedure)	Defined as final TIMI flow \> 3 (TIMI 0: absence of any integrate flow beyond the coronary occlusion; TIMI 1: faint antegrade flow beyond the coronary occlusion with incomplete filling of the distal coronary bed; TIMI 2: delayed flow beyond the coronary occlusion with complete filling of the distal coronary bed; TIMI 3: normal flow with complete filling of the distal coronary bed)

Secondary

Measure	Time frame	Description
Target Lesion Failure	12 moths	Combination of cardiac death, target vessel MI and clinically target lesion revascularization

Countries

Italy, Spain

Contacts

Primary ContactGiulio Piedimonte, MD

giulio.piedimonte@gmail.com+393201764900

Backup ContactEnrico Cerrato, MD

enrico.cerrato@gmail.com+393479317104

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026