Acne Vulgaris
Conditions
Brief summary
To compare the efficacy of 25% trichloroacetic acid peel versus 30% salicylic acid peel in mild to moderate acne vulgaris. Study Design: Randomized Control Trial. Place And Duration of Study: Department of Dermatology, CMH Abbottabad from 01 Jun 2022 to 30th Nov, 2022. Methodology: A total of 60 patients presented with mild or moderate acne vulgaris were randomized into two groups comprising 30 patients in each group and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Patients in Group A were treated with 25% TCA peel whereas patients in Group B were treated with 30% SA peel. At the end of therapy after 12 weeks, evaluation of active acne was done by individual lesion counts (comedones, papules and pustules) and calculation of the Michaelsson acne score (MAS).
Interventions
DRUG25% TRICHLOROACETIC ACID
Patients of group A were treated with 25% TCA peel and patients at 2-week intervals for a total of 12 weeks. Clinical evaluation was done at the end of therapy after 12-weeks of treatment.
DRUG30% salicylic acid
Patients of group B were treated with 30 % salicylic acid peel and patients at 2 weeks interval for a total of 12 weeks.clinical evaluation was done at the end of therapy after 12 weeks of treatment
Sponsors
Combined Military Hospital Abbottabad
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
13 Years to 22 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with mild or moderate facial acne vulgaris presented in dermatology opd
Exclusion criteria
* Patients with grade III or IV acne vulgaris * patients taking any acne medications or had taken oral or topical medications in the past 4 weeks * pregnant female patients or nursing a baby * patients with known hypersensitivity to the formulations used in the study or a history of photosensitivity * hypertrophic scars, keloidal tendency, active or recurrent herpes simplex infection * active dermatosis * unrealistic expectations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effectiveness of 25 % trichloroacetic acid peel versus 30 % salicylic acid peel in the treatment of mild to moderate acne vulgaris | 12 weeks | Michaelson acne scores (MAS) Michaelson acne scores (MAS) was used to measure the effectiveness of both peels |
Countries
Pakistan
Outcome results
None listed