Multiple Sclerosis
Conditions
Brief summary
The current study aims to test an online, non-restrictive diet among persons with multiple sclerosis (MS). Diet is the number one searched second-line therapy among persons with MS, however there are currently no established dietary approaches to improve health and wellbeing among persons with MS. Participants will complete the 8-week diet program using an online application. The primary research question is whether the diet program is acceptable and can improve general health indicators including cholesterol, glucose, body weight, body fat as well as MS symptoms (i.e., walking, cognition, fatigue, and quality of life).
Interventions
BEHAVIORAL800g Challenge
The intervention will involve 8 weeks of an online diet program. Outcomes testing will occur at baseline and post-intervention (following 8 week diet program). During the first 4 weeks, participants will receive educaitonal material and log their daily points in an online application and attend a weekly check-in call with members of the research team. During weeks 5-8, participants will log their daily points in the online application.
Sponsors
University of North Texas, Denton, TX
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* age 18-70 years * a self-reported diagnosis of multiple sclerosis * relapse free in past 30 days * non-pregnant * willing and able to visit University of North Texas on two testing occasions
Exclusion criteria
* electronic medical implant, such as a heart pacemaker or an implantable cardioverter defibrillator (ICD)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body Fat | From recruitment to end of 8 week intervention | Change in Body Fat Percentage |
| Metabolic Health | From recruitment to end of 8 week intervention | Fasted Cholesterol and Gloucose |
| Body Weight | From recruitment to end of 8 week intervention | Change in Body Weight |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive Assessments | From recruitment to end of 8 week intervention | Change in the Brief International Cognitive Assessment in MS Scores. Scores range from 0-208 with higher scores indicating greater cognitive functioning. |
| Health-Related Quality of Life | From recruitment to end of 8 week intervention | Change in SF-12 Scores. Scores range from 0-100 with higher scores indicating greater health-related quality of life. |
| Fatigue | From recruitment to end of 8 week intervention | Change in Fatigue Severity Scale Scores. Scores range from 1-7 with higher scores indicating greater fatigue. |
| 6-Minute Walk | From recruitment to end of 8 week intervention | Change in 6-Minute Walk Distance |
| 25-Foot Walk | From recruitment to end of 8 week intervention | Change in 25-Foot Walk Speed |
Other
| Measure | Time frame | Description |
|---|---|---|
| Acceptability of Intervention | From recruitment to end of 8 week intervention | Participants ratings of satisfaction with the diet program. Scores range from 1-5 with higher scores indicating greater satisfaction. |
Countries
United States
Outcome results
None listed