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Fall, Fracture and Frailty

Risk Factors for Fall and Fracture - A Cohort Study of Fall-related Factors Obtained in Routine Orthopaedic Fracture Care

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05712252
Acronym
FFF
Enrollment
1200
Registered
2023-02-03
Start date
2023-02-01
Completion date
2027-09-06
Last updated
2025-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fall Injury, Frailty, Hip Fractures, Osteoporosis, Osteopenia, Risk Reduction

Keywords

Falls, Fracture, Frailty, Orthogeriatric

Brief summary

This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation. Through better understanding 'falling phenotype', the ultimate aim is to prevent future complications, as well as new falls and fractures in the growing older population.

Detailed description

Background: The knowledge of risk factors for falls and fractures amongst older individuals are enormous, still identification of fallers and prevention of falls is not part of Swedish standard of care. Some risk factors are more or less overlooked, such as alcohol consumption, orthostatic reactions, as are increased risks related to common medications such as certain antidepressants, opioids and sedatives. Although functional activity and frailty scores have been suggested to be potential predictors of adverse events, length of hospital stay and mortality, the use of standardized questionnaires has not been implemented in routine care in Sweden. Furthermore, outcomes after fragility fractures, a well known consequence of falls among older individuals, are continuously poor, although palpable improvements have been reached regarding surgical treatment. Are there other factors that are equally or more decisive for the global outcome from the patient's point of view? Material & Methods: In this prospective observational cohort study, all in-patients treated due to a fall-related trauma (fracture, dislocation or contusion) at the Department of Orthopaedics, Skane University Hospital Malmö, aged 65 years or older will be invited to participate during a 1-year study period. In all participants, a standard package of blood samples, temperature, measurement of orthostatic blood pressure and grip strength, grading of frailty and activity will be routinely obtained.

Interventions

None listed

Sponsors

Region Skane
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 65 years or older at the time of admission. * Admitted to Orthopaedic ward at due to fall, with or without a fracture.

Exclusion criteria

* Severe head trauma or other severe non-orthopaedic trauma. * Other condition requiring ward at other department (CCU, ICU) \>24 hours. * Moribund individuals with palliative care only. * Declined to participate * Fall \> 7 days before admission * Residence outside the region (lack of follow-up)

Design outcomes

Primary

MeasureTime frameDescription
MortalityOne year after admission to hospitalThe number of deaths during follow-up
Re-admissionOne year after admission to hospitalNumber of re-admissions to emergency centre or in-patient ward due to a new fall (primarily) or complications related previous fall/fracture
Other adverse eventsOne year after admission to hospitalOther adverse events that are not included in outcome measure 1 or 2, such as infection, new falls, fractures, or complications from previous fall/fracture, or other medical complications. These can be further grouped by whether the events occur in in-patient or out-patient care.

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026