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Risk Factors for Postoperative Pancreatic Fistula Following Non-traumatic Pancreatic Surgery. Retrospective Observational Study.

Risk Factors for Postoperative Pancreatic Fistula Following Non-traumatic Pancreatic Surgery. Retrospective Observational Study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05711433
Enrollment
347
Registered
2023-02-03
Start date
2014-07-01
Completion date
2022-09-01
Last updated
2023-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreas Neoplasm

Brief summary

Postoperative pancreatic fistula is a potentially fatal sequela with substantial morbidity and mortality. A retrospective observational study was conducted in the surgical unit of Zagazig university hospital . Three hundred forty-seven patients were admitted with a clinical diagnosis of pancreatic fistula following both open and laparoscopic approaches for pancreatic benign and malignant tumors.

Detailed description

Postoperative pancreatic fistula is a potentially fatal sequela with substantial morbidity and mortality. POPF incidence and risk factors vary. A retrospective observational study was conducted in the surgical unit of Zagazig university hospital . Three hundred forty-seven patients were admitted with a clinical diagnosis of pancreatic fistula following both open and laparoscopic approaches for pancreatic benign and malignant tumors.

Interventions

PROCEDUREpancreatic surgery

pancreaticoduodenectomy and distal pancreatectomy

Sponsors

Zagazig University
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* \> 18 years, * both sexes, * respectablee pancreaticoduodenal tumors, or chronic pancreatitis

Exclusion criteria

* \<18 years, * Patients who underwent total pancreatectomies, * Patients discovered intraoperatively to be fixed to portal vein or superior mesenteric artery, traumatic pancreatic surgeries, postoperative associated gastric or biliary leak, pancreaticoduodenal cancers infiltrating the colon, stomach or liver.

Design outcomes

Primary

MeasureTime frameDescription
incidence of postoperative pancreatic fistula3.5 yearsan amylase level in the fluid collected from the drain on the third postoperative day (POD) that was \> three times the serum amylase level

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026