Caudal Versus S1 Transforaminal Epidural Steroid Injection for the Treatment of Unilateral S1 Radiculopathy

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05711121

Enrollment

Registered

2023-02-02

Start date

2022-01-01

Completion date

2023-03-31

Last updated

2023-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbosacral Radiculopathy

Keywords

epidural injection, radicular pain, disc herniation, lumbosacral radiculopathy, transforaminal injection, caudal injection

Brief summary

To compare the efficacies of two different interventional techniques (Caudal epidural steroid injection and S1 transforaminal epidural steroid injection) for the treatment of unilateral S1 radiculopathy.

Detailed description

Epidural steroid injections are commonly performed for the treatment of radicular pain resulting from a disc herniation. There are 3 different methods to deliver steroids to epidural area which are caudal, interlaminar and transforaminal routes. Lower lumbar and sacral radiculopathies can be managed with caudal epidural steroid injection which is generally quite easier to perform in comparison to transforaminal injection. Transforaminal epidural injection provides injectate to reach anterior epidural area and is the most target specific technique among others. In the present study investigators aim is to compare the success rates of these two different procedures regarding unilateral S1 radiculopathy. The patients referring to the pain medicine outpatient clinic of a university hospital for unilateral radicular pain and diagnosed S1 radiculopathy were planned to be randomized into these two different intervention groups.

Interventions

PROCEDURETransforaminal epidural steroid injection

Fluoroscopy-guided transforaminal epidural injection for radicular pain resulting from a disc herniation.

PROCEDURECaudal epidural steroid injection

Fluoroscopy-guided caudal epidural injection for radicular pain resulting from a disc herniation.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Masking description

Patients and the investigator assessing the treatment results were blinded to the injection technique.

Intervention model description

Patients having radicular pain were randomized to either caudal or transforaminal epidural injection group

Eligibility

Sex/Gender

ALL

Age

20 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Unilateral radicular pain resulting from a paracentral L5-S1 disc herniation causing S1 nerve root compression.

Exclusion criteria

* History of previous surgery, pregnancy, neurological disorders, bleeding diathesis, contrast medium allergy, spinal disorders, rheumatologic diseases

Design outcomes

Primary

Measure	Time frame	Description
50 percent pain relief	3 months	Number of patients having at least 50 percent pain relief

Secondary

Measure	Time frame	Description
Oswestry Disability Index	3 months	Improvement in disability scores, 0 is the best, 100 is the worst score.
Procedure time	during procedure	The overall ease of application regarding procedure time.
Radiation exposure	during procedure	The exposed radiation dose during the procedures

Countries

Turkey (Türkiye)

Contacts

Primary ContactEkim Can Ozturk, M.D.

ekimtrilogy@gmail.com+905448294239

Backup ContactSavas Sencan, Assoc. Prof.

savas-44@hotmail.com+905370665713

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026