Cortical Processes During Walking Post-stroke

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05710029

Enrollment

Registered

2023-02-02

Start date

2023-05-01

Completion date

2024-06-30

Last updated

2025-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, Acute, Walking, Difficulty

Keywords

Walking, Stroke, EEG, Assistance

Brief summary

The study aims to use novel mobile imaging techniques with high-density electroencephalography (EEG) to quantify cortical processes synchronized to the biomechanics of walking. Here, the study has two aims - the primary aim is to quantify the cortical processes that contribute to gait dysfunction early post-stroke, and the second aim is to determine how cortical processes are mediated by mechanical assistance during early gait training post-stroke. Participants will wear an electroencephalography (EEG) cap to measure brain activity and other non-invasive physiological sensors. Participants will be asked to perform different tasks, such as walking at different speeds and walking with different levels of body weight support.

Detailed description

This study will recruit 15 subacute post-stroke individuals and 15 age-matched neurotypical individuals between the age of 18-80 years old.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

for post-stroke patients: * Participants will have a unilateral brain lesion within six months prior to participation in this project; * Paresis confined to one side; * Ability to walk for 10 meters continuously; * Absence of severe cognitive dysfunction as demonstrated by a Mini-Mental score greater than 24; * Absence of severe concurrent medical problems; * Ability to provide informed consent.

Exclusion criteria

for age-matched adults: * Any major neurological, cardiovascular, orthopedic, and psychiatric diagnoses

Design outcomes

Primary

Measure	Time frame	Description
Brain activity during walking measured by EEG	through study study completion, an average of 2 years	Changes in brain activity during walking with different levels of weight support

Countries

United States

Outcome results