Hypoplastic Left Heart Syndrome
Conditions
Brief summary
This project has several objectives ranging from clinical data analysis to computational simulations as listed below: 1. Retrospective review of all patients with HLHS treated surgically and followed medically at the IRCCS Policlinico San Donato aiming to assess the SEVR after each step of Norwood palliation to analyze its influences on: * Mortality; * Occurrence of adverse events; * Outcome of the three-staged palliation; 2. Creation of a prospective registry that will enroll all patients surgically treated for HLHS at the IRCCS Policlinico San Donato.
Interventions
None listed
Sponsors
IRCCS Policlinico S. Donato
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato.
Exclusion criteria
* Patients with any type of atrioventricular discordance. * Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato before March 2019.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality during the hospital stay and after the discharge | 5 year | death, cardiovascular arrest |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of adverse events registered during the follow-up. | 5 year | Patients will be followed prospectively with their normal routine cardiological follow-up for 5 years |
Other
| Measure | Time frame | Description |
|---|---|---|
| Number of adverse events at the three-staged palliation (short and long-term mortality) | 5 year | Patients will be followed prospectively with their normal routine cardiological follow-up aiming to capture adverse events and clinical status. |
Countries
Italy
Outcome results
None listed