Heparin Lock, Normal Saline, Port-a-cath Occlusion
Conditions
Brief summary
Purpose: An evidence implementation of a randomized controlled trial for whether there is the difference in intermittent flushing 0.9% normal saline and heparin? Design: a single-blind randomized controlled trial Method: This study is based on the 5A (Ask, Acquire, Appraise, Apply, Audit) of evidence health care step, and design randomized controlled trial for evidence implementation. We will include inpatients over 20 years-old adults in New Taipei City TuCheng Hospital, Taiwan, who need administration medicine by port-a-catcher. The sample size is 192 according to G-power software. Random allocation software has using for block randomization, would assign to group A: flushing with 0.9% normal saline 10ml, group B: flushing with 0.9% normal saline 20ml, and group C: flushing with heparin 100 USP/ml. SPSS 20.0 software for statistical analysis, mean or standard deviation, one- way ANOVA would use.
Interventions
DRUGNormal Saline Flush 20 ml
Normal Saline Flush 20 ml
DRUGNormal Saline Flush 10 ml
Normal Saline Flush 10 ml
DRUGHeparin Flush (1000 USP, 10ml)
Heparin Flush (1000 USP, 10ml)
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Non-pediatric inpatients over 20 years of age with PAC placed for any disease and who need medication during hospitalization.
Exclusion criteria
History of PAC obstruction, continuous high volume drip via PAC, taking anticoagulant or antiplatelet agents, abnormal blood coagulation, pregnancy or contraceptive use, specified flushing solution by case
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| port-a-cath occlusion | in hospitalized (during admission), up to 12 weeks | failure to infusion fluid |
| port-a-cath infection | in hospitalized (during admission), up to 12 weeks | blood culture from port-A show bacterial growth |
Outcome results
None listed