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A Prospective Study of Surgical Treatment Strategies for Chordoma

A Prospective Study of Surgical Treatment Strategies for Chordoma

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05707767
Enrollment
100
Registered
2023-02-01
Start date
2023-02-01
Completion date
2024-09-30
Last updated
2023-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chordoma of Spine, Surgery

Keywords

chordoma

Brief summary

Chordoma is a rare but locally invasive cancer that arises from the embryonic notochord. Total resection is challenging in mobile spine because of the complex anatomy and bone invasion.

Interventions

Patients undergo resection surgery in our hospital.

Sponsors

Xuanwu Hospital, Beijing
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Between the ages of 18 and 70 ys, * With a diagnosis of chordoma confirmed by pathology, * Undergone surgical treatment in our hospital, * Available for clinical follow-up and agree to long-term clinical follow-up and sign informed consent.

Exclusion criteria

* Suffer from other tumors, * Suffer from cardiovascular disease, cerebrovascular disease, or immune system disease.

Design outcomes

Primary

MeasureTime frameDescription
Excision Extension1 week after surgery.Clinical and radiographic assessments of excision extension of tumor.

Secondary

MeasureTime frameDescription
OS (Overall Survival)2 yearsOverall Survival of patient underwent surgery.
PFS (Progression-Free Survival)2 yearsProgression-Free Survival of patient underwent surgery.
DFS (Disease Free Survival)2 yearsDisease Free Survival of patient underwent surgery.
ORR (Objective Response Rate)2 yearsObjective Response Rate of patient underwent surgery.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026