Autonomic Nervous System, Cerebral Autoregulation, Healthy
Conditions
Keywords
autonomic nervous system, heart rate variability, cerebral autoregulation, peripheral resistances
Brief summary
The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability. To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge. The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.
Interventions
DIAGNOSTIC_TESTactive standing
Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing
Sponsors
IRCCS Policlinico S. Donato
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* age \>18 * sinus rhythm * informed consent signed
Exclusion criteria
* age \<18 * presence of autonomic nervous system diseases or dysfunctions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the state and interactions of autonomic function and cerebrovascular control | 12 months |
Countries
Italy
Contacts
CONTACTVlasta Bari, PhD
Outcome results
None listed