Overweight and Obesity
Conditions
Brief summary
The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.
Interventions
BEHAVIORALResistance exercise training + weight loss group
Doing resistance exercises as well as following the weight watchers weight loss programme for a 12-week period
BEHAVIORALWeight loss only group (WL)
Only following the weight watchers weight loss programme for a 12-week period
Sponsors
University of Glasgow
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)
Masking description
Members of the research team that perform measurements are blinded to group allocation.
Intervention model description
Randomised controlled pilot trial with two groups, resistance exercise + weight loss group and weight loss only group.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Obesity or overweight (BMI ≥ 25kg/m2). * Passing the Physical Activity Readiness Questionnaire (PAR-q+)
Exclusion criteria
* Currently take part in more than 1.5 hours of structured exercise per week. * Having recently (\<6 months) taken part in any resistance exercise training, taking any medications known to affect weight loss. * Actively engaged in a weight loss programme, having lost more than 2kg weight in the last 6 months. * Any other reason which would limit ability to perform the exercises and outcome measurements safely.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in whole body lean mass | Change from baseline to 12 weeks | whole body lean mass measured via bio-electrical impedance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in functional physical abilities | Change from baseline to 12 weeks | A 30-second sit-to-stand test measured functional abilities |
| Change in knee extensor maximal isometric torque | Change from baseline to 12 weeks | Knee extensor maximal isometric torque measured during a maximal voluntary contraction |
| Change in grip strength | Change from baseline to 12 weeks | Grip strength measured with a hand held dynamometer |
| Change in body mass | Change from baseline to 12 weeks | body mass measured on scales |
| Change in vastus lateralis muscle thickness | Change from baseline to 12 weeks | Muscle thickness of the vastus lateralis muscle measured via ultrasound |
| Change in whole body fat mass | Change from baseline to 12 weeks | whole body fat mass measured via bio-electrical impedance |
Countries
United Kingdom
Outcome results
None listed