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Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05700994
Enrollment
1283
Registered
2023-01-26
Start date
2023-11-13
Completion date
2026-09-30
Last updated
2026-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methamphetamine Abuse

Brief summary

The main goal of this study is to tests the effect of incentivizing achievement of self-identified, personal harm reduction goals (Contingency management or CM) compared with standard of care (peer harm reduction service with incentives for peer visits) to increase the reach and effectiveness of methamphetamine (MA) harm reduction services.

Detailed description

Using a hybrid type 1 effectiveness-implementation framework and stepped-wedge design, this study will randomize eighteen community-based peer harm reduction sites to provide contingency management incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals) versus standard of care contingency management (i.e. incentives for peer encounter attendance).

Interventions

BEHAVIORALPeer Contingency Management

Participants allocated to peer-facilitated contingency management will receive incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals)

BEHAVIORALStandard of Care Contingency Management

Participants allocated to standard of care contingency management will receive incentives for peer encounters.

Sponsors

Comagine Health
CollaboratorOTHER
Oregon Health Authority
CollaboratorOTHER
Oregon Health and Science University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

This is a cluster-randomized pragmatic trial using a hybrid type 1 effectiveness-implementation framework and stepped-wedge design.

Eligibility

Sex/Gender
ALL
Age
18 Years to 105 Years
Healthy volunteers
No

Inclusion criteria

This intervention is at the site level. Community-based organization sites are eligible if they: * Use peer support specialists to provide direct outreach and harm reduction services to people who use drugs * Are willing to be trained in the two strategies for peer-facilitated contingency management Clients who: * Age 18 and older * Any stimulant (methamphetamine, cocaine) use in the past 30 days * Willing to accept peer services * Willing to complete initial and follow-up assessments with peer * Able to communicate in English or Spanish

Exclusion criteria

Community-based organization sites who: * Do not use peer support specialists to provide direct outreach and harm reduction services to people who use drugs * Are not willing to be trained in the two strategies for peer-facilitated contingency management Clients who: • Present any danger or threat of violence to peers

Design outcomes

Primary

MeasureTime frameDescription
Number of participants who overdose6 months from baselineTest the impact of incentives for achieving self-identified, personal harm reduction goals on the likelihood of overdose among people using methamphetamine at 6 months from enrollment identified through completed assessment.
Number of participants who achieve self-identified goals6 months from baselineDetermine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with harm reduction services at 6 months from enrollment identified through completed assessment.
Number of participants who engage in substance use disorder treatment6 months from baselineDetermine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with treatment services at 6 months from enrollment identified through completed assessment.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026