Acute Pain, Local Anesthetic, Postoperative Analgesia, Thoracic Paravertebral Block, Thoracotomy
Conditions
Brief summary
Thoracotomy is one of the most painful operations known. Therefore, it causes severe acute pain. If pain is not controlled, it increases the frequency of postoperative pulmonary complications and postoperative morbidity. It can even cause chronic pain in the future. Thoracic epidural analgesia (TEA) is the gold standard method in the treatment of pain after thoracotomy. Thoracic paravertebral block (TPVB) is known as the most effective method after TEA. The fact that TPVB has fewer side effects than TEA increases the use of TPVB. There is no consensus on the dose of analgesia in studies. In the literature, volumes between 20 ml and 30 ml are frequently used for TPVB in recent years. This study, it was aimed to compare the efficacy of 20 ml, 25 ml, and 30 ml volumes of TPVB with local anesthetic at the same concentration (0.25% bupivacaine) on postoperative analgesia in patients undergoing thoracotomy.
Interventions
PROCEDURETPVB with 20 ml
The thoracic paravertebral block will be applied to the patients with 20 ml of 0.25% bupivacaine under real-time ultrasound guidance.
PROCEDURETPVB with 25 ml
The thoracic paravertebral block will be applied to the patients with 25 ml of 0.25% bupivacaine under real-time ultrasound guidance.
PROCEDURETPVB with 30 ml
The thoracic paravertebral block will be applied to the patients with 30 ml of 0.25% bupivacaine under real-time ultrasound guidance.
Sponsors
Ankara City Hospital Bilkent
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 18 to 80 years old * American Society of Anesthesiologists (ASA) physical status I-II-III * BMI 18 to 40 kg/m2 * Elective thoracotomy surgery
Exclusion criteria
* Patient refusing the procedure * Emergency surgery * History of chronic opioid or analgesic used
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain Scores | 1st hour after surgery | Pain will be assessed at the first-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Morphine Consumption | 24 hours after surgery | Morphine consumption for 24 hours will be recorded |
Countries
Turkey (Türkiye)
Contacts
Primary ContactEmine N ZENGİN
Outcome results
None listed