Healthy Lifestyle
Conditions
Keywords
Creatine, Strength, Body Composition, Athletic performance, Nutritional supplementation
Brief summary
A triple-arm double-blinded placebo-controlled repeated-measures randomized clinical trial in Colombian elite team-sport athletes. The aim is to evaluate the effects on strength-related parameters and body composition after eight weeks of supplementation with creatine monohydrate (CrM) and creatine hydrochloride (Cr-HCl). The study will be reported following the Consolidated Standards of Reporting Trials (CONSORT) extension to Multi-Arm Parallel-Group Randomized Trials. All variables will be measured at baseline and after eight weeks.
Detailed description
Creatine monohydrate (CrM) is the most studied nutritional supplement and, therefore, one of the most popular ergogenic nutritional aids for athletes. Studies have shown that CrM supplementation increases intramuscular creatine concentrations which enhances exercise performance and improves body composition in different populations (from young athletes to older adults). It is important to note that the U.S. Food and Drug Administration (FDA) have recognized CrM as a safe ingredient (Generally Recognized as Safe, GRAS - No. GRN 000931). In spite of this, other forms such as creatine chloride (Cr-HCl) have been marketed as a more bioavailable sources of creatine. Since there are not studies that rigorously compare the effects of CrM versus Cr-HCl on physical performance and body composition, the aim of this study is to evaluate the effects of a 8-week supplementation protocol with the two forms of creatine (comparing to placebo) on neuromuscular strength and body composition in Colombian elite team-sport athletes.
Interventions
DIETARY_SUPPLEMENTCreatine Monohydrate
The CrM group supplemented the diet with five grams of micronized creatine monohydrate per day for eight weeks. The CrM supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
DIETARY_SUPPLEMENTPlacebo
A placebo group intakes five grams of maltodextrin daily throughout the study. The placebo supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
DIETARY_SUPPLEMENTCreatine Hydrochloride
The Cr-HCl group supplemented the diet with five grams of micronized creatine monohydrate per day for eight weeks. The Cr-HCl supplement was fully dissolved in ≈500 mL of water and drank immediately after each training session (in the morning on non-training days).
Sponsors
INDEPORTES Antioquia
CES University
Dynamical Business and Science Society - DBSS International SAS
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Masking description
This was a double-blinded clinical trial since participants and those assessing the outcomes were blinded to the intervention. All groups were given small metallic plastic bags with five grams of powder identical in size, shape, and color but the placebo contained maltodextrin (Tecnas S.A., Medellín, Colombia).
Intervention model description
This was a double-blinded placebo-controlled repeated-measures randomized clinical trial in elite team-sport athletes with three arms in parallel.
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Practicing team sports at the competitive level (handball and softball) * Having at least one year of competitive sports training experience (including strength training at least three times a week), * Being attended at INDEPORTES Antioquia.
Exclusion criteria
* Those who do not wish to participate voluntarily (do not sign informed consent), * Those who were taking nutritional supplements (including creatine) eight weeks prior to the start of the study, * Those who had a diagnosed pathology or health issues.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lower-limb muscle power | Eight weeks | Countermovement and drop jump will be performed on contact mat (height in centimeters and time of flight in seconds) |
| Neuromuscular strength | Eight weeks | The load-velocity profile in squat and bench press exercises will be obtained with a linear position transducer (load in kilograms versus mean propulsive velocity in meters per second). |
| Upper-limb muscle strength | Eight weeks | Maximal shoulder external and internal strength will be measure with a isokinetic dynamometer. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body composition | Eight weeks | Body composition was measured using dual-energy x-ray absorptiometry. Fat mass and lean mass in kilograms were reported. |
Countries
Colombia
Outcome results
None listed