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Angiography Derived Index of Microcirculatory Resistance in Patients With Acute Myocardial Infarction

Angiography Derived Index of Microcirculatory Resistance in Patients With Acute Myocardial Infarction

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05696379
Enrollment
5000
Registered
2023-01-25
Start date
2017-06-01
Completion date
2022-05-31
Last updated
2023-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction (AMI)

Brief summary

Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of acute myocardial infarction (AMI) patients, and has been shown to be associated with poor prognosis. Angiography derived index of micro-circulatory resistance (Angio-IMR) is a novel pressure-wire free approach to assess coronary microvascular disease with great diagnostic performance. The current study will further investigate the prognostic value of Angio-IMR in patients with AMI in multicenter retrospective cohort.

Interventions

OTHERAngiography derived index of micro-circulatory resistance (Angio-IMR)

Angiography derived index of micro-circulatory resistance (Angio-IMR) post percutaneous coronary intervention.

Sponsors

Shengjing Hospital
CollaboratorOTHER
RenJi Hospital
CollaboratorOTHER
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Acute myocardial infarction patients who underwent successful percutaneous coronary intervention

Exclusion criteria

* No appropriate coronary angiography images (inferior image quality, image loss, severe arteries overlap, or significant artifact) * Previous coronary artery bypass graft

Design outcomes

Primary

MeasureTime frameDescription
Cardiac death or readmission for heart failure in 1 month1 monthIncidence of cardiac death or readmission for heart failure during first 1 month follow-up.
Cardiac death or readmission for heart failure in 6 months6 monthIncidence of cardiac death or readmission for heart failure during first 6 months follow-up.
Cardiac death or readmission for heart failure in 1 year1 yearIncidence of cardiac death or readmission for heart failure during first 1 year follow-up.
Cardiac death or readmission for heart failure in 2 years2 yearIncidence of cardiac death or readmission for heart failure during first 2 years follow-up.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026