Pulmonary Aspiration of Gastric Contents
Conditions
Keywords
Preoperation fasting, Anaesthesia, Children, Enteral feeding
Brief summary
The primary objective of the study is to compare the risk of increased stomach contents after tube feeding (Enteral feeding) 6 and 4 hours before anesthesia using antrum measured by ultrasound.
Detailed description
Children must fast for a certain period of time before anesthesia and surgery to reduce the risk of food residues being vomited up and ending up in the trachea (so-called aspiration). But there are disadvantages to fasting for a long time before an operation, for example the blood sugar level can drop and the body can become dehydrated. Small children risk such side effects to a greater degree than adults, and therefore international work is underway to revise the rules for fasting before surgery. Enteral feeding children are a special risk group because they are usually completely dependent on tube feeding for nutrition and fluid intake.
Interventions
PROCEDUREPreoperative fasting instruction
Patients parents instructed to stop enteral feeding at a specified time before predicted anesthesia induction
Sponsors
Uppsala University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
Computerized randomization. Randomization outcome distributed via sealed envelopes. Randomization key stored on secure server.
Intervention model description
Randomized controlled trial.
Eligibility
Sex/Gender
ALL
Age
6 Months to 12 Years
Healthy volunteers
No
Inclusion criteria
Child on intermittent or continuous enteral nutrition, scheduled for elective procedure requiring general anesthesia
Exclusion criteria
Moderate to severe gastrointestinal motility disorder Emergency surgery Anatomical risk factor for pulmonary aspiration such as achalasia or bowel obstruction Parents cannot understand study information due to language barrier
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| CSA | Immediately before anesthesia induction | Gastric antral surface area |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Suctioned GCV | Immediately after intubation | Gastric content volume suctioned through nasogastric tube after induction |
Countries
Sweden
Contacts
Primary ContactPeter Frykholm, MD, PhD
Backup ContactAli-Reza Modiri, PhD
Outcome results
None listed