Orthodontic Appliance Complication
Conditions
Brief summary
Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time. Low Level Laser Therapy(LLLT) applied in Orthodontic Tooth Movement, which stimulates formation of osteoclast-like cells expression in vitro. Osteoclast can be served as an index for tooth movement. Increasing the number of osteoclast will increase bone formation and tooth movement. We plan to find a useful clinical protocol to improve the efficiency of orthodontic tooth movement. Test low energy laser in vitro. Find an effective wavelength and irradiation time to stimulate formation of osteoclast. Develop an useful protocol that clinical orthodontist could follow and reduce orthodontic treatment time.
Interventions
DEVICELow Level Laser Therapy
Low level laser therapy could provide energy to trigger cell differentiation.
OTHERPlacebo
Placebo
Sponsors
China Medical University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DEVICE_FEASIBILITY
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients with good oral hygiene * 18 years old * Patients who required bilateral canine retraction into the extracted premolar
Exclusion criteria
* Serious medical history * Poor oral hygiene * Previous orthodontic treatment * Orthognathic surgery or syndromic patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Orthodontic tooth movement | 1-6month | the distance between canine and premolar |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| bone density after Orthodontic tooth movement | 1-6month | bone density change around canine |
Countries
Taiwan
Outcome results
None listed