Sarcopenia
Conditions
Keywords
sarcopenia, elderly, exercise program, explainable artificial intelligence
Brief summary
Sarcopenia is a geriatric condition characterized by a progressive decrease in skeletal muscle content and loss of muscle function. Resistance exercise, Taichi exercise and the hybrid exercise program consisting of the two aforementioned methods have been demonstrated could increase the skeletal muscle mass of the elderly with sarcopenia. However, note that the above contents may be performed in a different order in a treatment, equally important but less well understood is the sequence in which it should be performed. Surprisingly, the exercise sequence has not been comprehensively investigated. Therefore, investigators designed a self-ordered exercise program combining resistance exercise, tai chi and a hybrid exercise program to investigate whether the decline in skeletal muscle area could be better overcome and the reversal of sarcopenia in elderly with sarcopenia.
Interventions
BEHAVIORALself-determine sequence exercise program
The Taichi exercise utilized the simplified eight styles of Taichi. The resistance training program consisted of three cycles. In the first cycle, investigators used a light load but high repetitions (ranging from 40% to 60% of one repetition maximum and 12-20 repetitions). During the second phase of our training, investigators raised the training load by doing sets of moderate intensity and a medium number of repetitions (ranging from 60% to 80% of one repetition maximum and 5-12 repetitions). In the third cycle, investigators aimed to improve the participants' maximal muscular resistance by using a greater training load and fewer repetitions (ranging from 70% to 85% of one repetition maximum and 5-8 repetitions).
BEHAVIORALresistance training
The resistance training program consisted of three cycles. In the first cycle, investigators used a light load but high repetitions (ranging from 40% to 60% of one repetition maximum and 12-20 repetitions). During the second phase of our training, investigators raised the training load by doing sets of moderate intensity and a medium number of repetitions (ranging from 60% to 80% of one repetition maximum and 5-12 repetitions). In the third cycle, investigators aimed to improve the participants' maximal muscular resistance by using a greater training load and fewer repetitions (ranging from 70% to 85% of one repetition maximum and 5-8 repetitions). Participants in the RTG completed four sets of each movement, with two to three minutes of rest between each set.
BEHAVIORALTaichi exercise and resistance training
The training of the Taichi exercise and resistance training group consisted of two cycles, the first cycle was aimed at learning and consolidating Taichi exercise, and the second cycle was aimed at improving and consolidating. The Taichi exercise and resistance training group was scheduled for 30 min of Taichi exercise per training. The resistance training program consisted of three cycles. In the first cycle, investigators used a light load but high repetitions (ranging from 40% to 60% of one repetition maximum and 12-20 repetitions). During the second phase of our training, investigators raised the training load by doing sets of moderate intensity and a medium number of repetitions (ranging from 60% to 80% of one repetition maximum and 5-12 repetitions). In the third cycle, investigators aimed to improve the participants' maximal muscular resistance by using a greater training load and fewer repetitions (ranging from 70% to 85% of one repetition maximum and 5-8 repetitions).
BEHAVIORALRandomly selected exercise program
Participants in the randomly selected exercise program group who chose Yijinjing exercise were required to complete one hour of Yijinjing exercise training, and those who chose Yijinjing exercise hybrid strength training had to complete half an hour of Yijinjing training. The resistance training program consisted of three cycles. In the first cycle, investigators used a light load but high repetitions (ranging from 40% to 60% of one repetition maximum and 12-20 repetitions). During the second phase of our training, investigators raised the training load by doing sets of moderate intensity and a medium number of repetitions (ranging from 60% to 80% of one repetition maximum and 5-12 repetitions). In the third cycle, investigators aimed to improve the participants' maximal muscular resistance by using a greater training load and fewer repetitions (ranging from 70% to 85% of one repetition maximum and 5-8 repetitions).
Sponsors
Northeast Normal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
60 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
1. satisfied the Asian screening criteria for sarcopenia by the Asian Working Group for Sarcopenia; 2. age higher than 60 but less than 75 years of age.
Exclusion criteria
1. with serious illness or breathing failure; 2. with neuro-muscular diseases; 3. taking medication that has an effect on the function of skeletal muscles; 4. with conditions relating to the neurological system or the mental health; 5. in another scheduled training plan.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Using quantitative CT to investigate the change of skeletal muscle area in sarcopenic elderly. | Month 6 | Participants will receive quantitative CT scans before and after the intervention to assess the change from baseline skeletal muscle area at 6 months. |
| Using a Jamar hydraulic hand dynamometer to investigate change of handgrip in sarcopenic elderly. | Month 6 | Participants will receive a handgrip strength test before and after the intervention to assess the change from baseline handgrip strength at 6 months. |
| Using a bioelectrical impedance body composition analyzer with a multifrequency device to investigate the change of relative skeletal muscle mass index in sarcopenic elderly. | Month 6 | Participants will receive a relative skeletal muscle mass index test before and after the intervention to assess the change from baseline relative skeletal muscle index at 6 months. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Collect participants' self-evaluation of their life state and physical state. | Month 6 | Participants were asked to write a self-assessment report of no more than 500 words before and after the intervention, including physical status and life status. |
| Collect video of participants throughout the intervention. | Month 6 | The entire intervention process was videotaped and video of the entire intervention process was collected from the participants. |
Countries
China
Outcome results
None listed