Ventilator Lung
Conditions
Keywords
mechanical power, volume controlled ventilation, pressure controlled ventilation
Brief summary
Comparison of mechanical powers produced at volume controlled and pressure controlled mechanical ventilation
Detailed description
The mechanical power created by mechanical ventilation, as a new concept, can enable to evaluate the effect of different components in the lung.Our aim in this study is to calculate mechanical power in different ventilation modes ( pressure controlled and volume controlled ventilation) and to compare them. To calculate the mechanical powers we will use Van der Meijden's mechanical power formula for pressure controlled ventilation and for volume controlled ventilation we will use Gattinoni's mechanical power formula. In the literature we haven't seen any publication comparing the mechanical power of two commonly used ventilation modes (volume controlled and pressure controlled ventilation)
Interventions
OTHERStarting with volume controlled ventilation and changing the ventilation mode every 20 minutes
group 1 starts with volume controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to pressure controlled ventilation after letting washout we take three consecutive measurements at pressure controlled ventilation and we will repeat this protocol during surgery
OTHERStarting with pressure controlled ventilation and changing the ventilation mode every 20 minutes
group 2 starts with pressure controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to volume controlled ventilation after letting washout we take three consecutive measurements at volume controlled ventilation and we will repeat this protocol during surgery
Sponsors
Istanbul University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* ASA1-2 , \>18 years old patients having upper abdominal surgery
Exclusion criteria
* chronic obstructive lung disease, interstitial lung disease * chronic renal failure * Child-Pugh \> 6 liver disease * Patients who don't give consent * NYHA \> 2 heart failure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| calculation of mechanical power changes in two different ventilation modes | change from at the beginning of surgery till the end of surgery | mechanical power will be calculated using the Van der Meijden's formula for pressure support ventilation and Gattinoni's formula for volume controlled ventilation and two mechanical powers will be compared |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| postoperative pulmonary complications | post-operative 7 days | postoperative pulmonary complication including pneumonia, acute lung injury, respiratory failure requiring reintubation |
| hospitalisation time | up to 20 days | up to 20 days |
Countries
Turkey (Türkiye)
Outcome results
None listed