Bariatric Surgery Complication, Gastroesophageal Reflux, Sleeve Gastrectomy
Conditions
Brief summary
This study aims to determine if preoperative EndoFlip measurement can effectively predict postoperative GERD-related quality of life and lower esophageal acid exposure.
Detailed description
Enrolled patients will be subjected to a pre-operative gastroscopy, 48-Hour Bravo pH study and EndoFlip. In addition, each patient will complete a GERD-related quality of life questionnaire (GERD-HRQL scale). One year after surgery, patients will undergo a follow up a gastroscopy, pH study, EndoFlip and the same quality of life questionnaire to predict the incidence of postoperative GERD and determine the effect of sleeve gastrectomy.
Interventions
PROCEDUREsleeve gastrectomy
Patients will be recruited for a sleeve gastrectomy according to the guidelines of the National Institute of Health.
Sponsors
Université de Sherbrooke
Laval University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
Before/after study design
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 65 years old
Exclusion criteria
* Hiatal hernia \> 2 cm at preoperative gastroscopy * Erosive esophagitis at preoperative gastroscopy * Barrett's metaplasia/dysplasia at preoperative gastroscopy * Revision surgery before the end of the study * Pregnancy during the study period * Actively bleeding esophageal varices
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| New-onset of gastroesophageal reflux disease | 12 months postoperatively | total time of esophageal acid exposure (minutes) |
Contacts
Primary ContactRinguette Vickie
Outcome results
None listed