Complication of Anesthesia, Complication of Surgical Procedure, Complication,Postoperative, COVID-19, Sars-CoV-2 Infection
Conditions
Brief summary
With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness. China 's epidemic prevention and control has entered a new stage to restore the normal functioning of society and basic medical services, On Dec, 7, China released a circular on further optimizing its COVID-19 response, announcing 10 new prevention and control measures.This has marked the watershed for sharply increased number of elective surgical patients diagnosed with COVID-19 during preoperativley, fully recovered or during recovery. Beijing faced a wave of omicron infection starting that would result in of a wide range of population infections. At which time there is limited evidence regarding the optimal timing of surgery following SARS-CoV-2 infection especially for omiron among Chinsese patients .This study intends to explore the relationship between the incidence of postoperative complications after elective surgery and COVID-19 infection in Peking Union Medical College Hospital, and provide data support for the policy formulation of elective surgical timing for patients after COVID-19 infection.
Interventions
PROCEDUREReceiving inpatient surgical intervention
Receiving inpatient surgical intervention in Peking Union Medical College Hospital
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1\. All patients having pre-operative SARS-CoV-2 infection diagnosis Dec 1st 2022 to Feb 28th 2023. \[The COVID-19 diagnosis is based on either (a) a positive RT-PCR nasopharyngeal swab, (b) positive antigen rest before surgery, or (c) clinical diagnosis made before surgery\].
Exclusion criteria
1. Patients diagnosed with SARS-CoV-2 infection on the day of surgery or during postoperative days. 2. Day surgery or outpatient surgery. 3. Patients unwilling to participate or provide COVID-19-related information.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perioperative complications | During the procedure | The composite primary outcome included pulmonary complications (pneumonia, acute respiratory distress syndrome, or acute respiratory failure, reintubation, unplanned use or prolongation of postoperative mechanical ventilation), cardiovascular complications (deep vein thrombosis, pulmonary embolism, myocardial infarction, newly onset arrhythmia, ischemic stroke, and acute kidney injury), and infectious complications other than pulmonary infection (urinary tract infection, surgical site infection, and sepsis). |
Other
| Measure | Time frame | Description |
|---|---|---|
| Readmission rate during 30 days after surgery | 30 days after operation | Readmission due to surgery complications during 30 days after operation |
| Postoperative mechanical ventilation time | During the procedure | Length of mechanical ventilation time after surgery |
| Mortality after operation | 1 month, 3 months, 6 months, 12 months after operation | Mortality after operation in 1 month, 3 months, 6 months, 12 months |
| Length of hospital stay | Immediately after discharge | Calculate the number of days the patient stays in the hospital. |
| the WHODisability Assessment Schedule (WHODAS 2.0) | 6 months after operation | * Step 1-Summing of recoded item scores within each domain. * Step 2-Summing of all six domain scores. * Step 3-Converting the summary score into a metric ranging from 0 to 100 (where 0=no disability; 100=full disability). |
| Brief Pain Inventory (BPI) | 6 months after operation | Brief Pain Inventory used to assess the intensity of pain |
| Intraoperative respiratory complication | During the surgery | Intraoperative respiratory complication: a composite of intraoperative bronchospasm, poor oxygenation, and reintubation. |
Countries
China
Outcome results
None listed