Wrinkle
Conditions
Brief summary
This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes. The 5 facial products in the regimen are a cleansing balm, a toner, a serum, a moisturizer. and an eye cream.
Interventions
OTHERCleansing Balm
DermResults Cleansing Balm w/ Avocado Oil twice daily
OTHERToning Essence
DermResults Advanced Toning Essence w/ Mineral Booster twice daily
OTHERFacial Serum
DermResults Advanced Serum w/ Hyaluronic Acid twice daily
OTHERMoisturizer
DermResults Advanced Moisturizer w/ Hyaluronic Acid twice daily
OTHEREye Cream
DermResults Advanced Eye Cream w/ Hyaluronic Acid twice daily
Sponsors
Arbonne
Integrative Skin Science and Research
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
35 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Men and women between the ages of 35 years old and 65 years old. * Must have fine lines and wrinkles around the eyes.
Exclusion criteria
* Individuals who are pregnant or breastfeeding. * Prisoners * Adults unable to consent * Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study. * Subjects using any topical retinoid, hydroquinone, kojic acid, bakuchiol, hyaluronic acid or benzoyl peroxide containing topical product within 2 weeks of starting study or any subject unwilling to refrain from washout prior to enrollment. * Subjects with any facial treatments in the past 6 months and who are unwilling to withhold facial cosmetic treatments during the study including botulinum toxin, injectable fillers, microdermabrasion, intense pulsed light (IPL), peels, laser treatments, acid treatments, tightening treatments, facial plastic surgery, or any other medical treatment administered by a physician or skin care professional which is designed to improve the appearance of facial skin. * Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Appearance of facial wrinkles | 8 weeks | Change in wrinkle severity measured by photographic analysis (BTBP 3D Camera System) |
| Change in skin pigmentation in the undereye area | 8 weeks | Change in skin pigmentation in the undereye area by Skin colorimetric analysis of pigment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Skin volume | 1 week | Change in skin volume/plumpness by photographic image analysis with BTBP 3D Camera System |
| Skin texture/roughness | 1 week | Change in the appearance of photographic analysis of texture/roughness with BTBP 3D Camera System |
| Skin hydration | 1 week | Change in skin hydration by SkinMoistureMeterSC measurement |
| Tolerability of products | 1 week | Questionnaire based self-assessment about the tolerability of the topical skin products |
| Appearance of facial wrinkles | Change in wrinkle severity measured by photographic analysis (BTBP 3D Camera System) | 4 weeks |
| Self-perception of skin parameters | 1 week | Survey based self-assessment of facial fine lines and wrinkles, skin smoothness, skin firmness |
| Transepidermal water loss | 1 week | Change in transepidermal water loss measurement with Vapometer |
Countries
United States
Outcome results
None listed