Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05688150

Enrollment

Registered

2023-01-18

Start date

2022-06-20

Completion date

2023-02-28

Last updated

2024-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis, Sarcopenia

Keywords

osteosarcopenia, sarcopenia, osteoporosis, geriatric medicine

Brief summary

This was a cross-sectional study. Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022 were recruited. Grip strength and appendicular skeletal muscle mass index were measured with a Jamar dynamometer and a bioimpedance analyser. Since most patients in our clinic are of Chinese ethnicity, the diagnostic criteria in the Consensus Update on Sarcopenia Diagnosis and Treatment by the Asian Working Group for Sarcopenia in 2019 was utilised. The diagnosis of sarcopenia was established by the presence of both low grip strength (Male: \< 28 kg, Female \< 18 kg) and low appendicular skeletal mass (Male: \< 7.0 kg/m2, Female: \< 5.7 kg/m2)

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 60 years old or above * Diagnosed with osteoporosis by: Fragility fracture or T-score ≤-2.5 SDs at any site on DXA scan and; * Able to read and write Chinese

Exclusion criteria

* Unable to maintain standing posture for bioimpedance analysis * Modified Functional Ambulation Classification (MFAC) ≤ IV * Incompetent in giving consent * Unable to follow instructions * Implanted with metal in any of four limbs * Implanted with pacemaker, implantable cardioverter defibrillator or any other types of electrical device

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of Sarcopenia	June - December 2022	The diagnosis of sarcopenia would be established by the co-existence of low grip strength and low appendicular skeletal muscle mass.
Grip strength	June - December 2022	Grip strength would be measured with Jamar digital dynamometer.
Appendicular Skeletal Muscle Mass Index	June - December 2022	Appendicular Skeletal Muscle Mass Index would be measured with bioimpedance analyzer.

Secondary

Measure	Time frame	Description
Association between BMI and Sarcopenia.	June - December 2022	BMI would be measured on clinic attendance.
Association between Bone Mineral Densities and Sarcopenia	June - December 2022	Bone mineral densities of spine and neck of femur would be extracted from the report of dual-energy X-ray absorptiometry.
Association between Frailty and Sarcopenia.	June - December 2022	Clinical Frailty Scale would be documented in clinical consultation.
Association between Charlson Comorbidities Index and Sarcopenia	June - December 2022	Components of Charlson Comorbidities Index would be extracted from medical record.

Countries

Hong Kong

Outcome results