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Residual or Recurrent Obstruction After Septal Myectomy

Residual or Recurrent Obstruction After Septal Myectomy in Young Children and Infants With Hypertrophic Cardiomyopathy

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05687487
Enrollment
56
Registered
2023-01-18
Start date
2013-01-01
Completion date
2021-02-01
Last updated
2023-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic Obstructive Cardiomyopathy

Keywords

Septal myectomy, Residual or recurrent obstruction, children and infants, hypertrophic obstructive cardiomyopathy

Brief summary

The goal of this observational study is to report the outcomes after septal myectomy in young children and infants and identify the mechanisms of residual or recurrent obstruction after surgery. in The main question\[s\] it aims to answer are: * What is the early and mid-term results of septal myectomy in young children and infants with severe and extensive obstructive hypertrophic cardiomyopathy (HCM)? * What are the mechanisms of residual or recurrent obstruction? Echocardiography and clinical course of children and infants under the age of 14 who underwent septal myectomy for hypertrophic obstructive cardiomyopathy from January 2013 to December 2020 will be followed up.

Interventions

None listed

Sponsors

Chinese Academy of Medical Sciences, Fuwai Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 14 Years
Healthy volunteers
No

Inclusion criteria

* Clinical diagnosis of hypertrophic obstructive cardiomyopathy (HOCM) * Age young than 14 years * Patients who have undergone septal myectomy

Exclusion criteria

* older than 14 years old; * secondary left ventricular hypertrophy (LVH) related to subaortic stenosis or aortic stenosis.

Design outcomes

Primary

MeasureTime frameDescription
deaththrough study completion, an average of 1 yearpostoperative death during follow-up

Secondary

MeasureTime frameDescription
recurrent obstructionthrough study completion, an average of 1 yearpostoperative recurrent obstruction during follow-up

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026