Central Serous Chorioretinopathy
Conditions
Brief summary
Central serous chorioretinopathy (CSC) is a common eye disease mainly involving the macular area, causing central visual acuity loss. Recently, subthreshold micropulse laser used in treating chronic CSC is proved to be safe and effective. However, some studies indicate that it's less effective than half dose photodynamic therapy (PDT). Certain physicians, including us, think that this may be related to micropulse laser parameters. Thus we need to explore better laser patterns to replace PDT in treating chronic CSC. The aim of this study is to compare the treatment effect of two different patterns of laser parameters (small and regular spot diameter) in treating chronic CSC. In this randomized, double blinded, controlled trial, by comparing the subretinal fluid regression ratio, central retinal thickness, macular microvisual field, macular vascular density, chroidal volume changes and visual acuity of two groups 6 months after micropulse laser treatment, we aim to evaluate the safety and efficacy of refined micropulse laser in treating chronic CSC.
Interventions
100μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months
200μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients age range 18-50 years * Patients diagnosed with chronic Central serous chorioretinopathy * Patients have signed informed consent
Exclusion criteria
* A history of other fundus diseases or refractive media opacity * Patients have underwent other treatment methods for chronic Central serous chorioretinopathy * Diopter\>-6D * A history of system diseases such as hypertension or diabetes * A history of using local or systemic corticosteroids
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subretinal fluid regression ratio | 6 months | Comparing the subretinal fluid regression ratio of two groups at 6 months follow-up |
| Central retinal thickness changes | 6 months | Comparing the central retinal thickness changes of two groups at 6 months |