The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Left Ventricle

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05685823

Enrollment

140

Registered

2023-01-17

Start date

2019-10-01

Completion date

2023-10-31

Last updated

2023-01-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Chronic Kidney Diseases, Fibrosis

Brief summary

The objective of this study is to evaluate a group of patients with chronic kidney disease in stages 3-5 by conventional 2D echocardiography, tissue Doppler techniques and speckle tracking - LV GLS and determine the correlation of ultrasound parameters with mortality. Additionally, fibrosis-related biomarkers will be studied in this population.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* eGFR \< 15 ml/min/1.73m2 (CKD - EPI) * NYHA class I-II * Hemodynamic stability

Exclusion criteria

* age \< 18 years old * poor acoustic window * atrial fibrillation * recent Acute Myocardial Infarction * pacemaker

Design outcomes

Primary

Measure	Time frame
Variation of GLS	3 years
All-cause mortality	3 years

Countries

Romania

Outcome results