Cancer, Pain, Substance Use
Conditions
Brief summary
Pain is one of the most prevalent symptoms during and after cancer. Pain can be the consequence of several situations (disease progression, surgery, and anticancer drugs). However, pain can frequently be associated with a substance use disorder (alcohol, tobacco, drugs, and illicit products such as cannabis). The relationship between substance use and pain is known to be complex and interdependent, i.e. pain can reinforce substance use and substance use can promote pain. However, few data in the literature are available on the use of psychoactive substances in relation to pain in the context of cancer (cancer patients and cancer survivors). Moreover, the scientific literature agrees on the fact that these elements are little studied and underestimated in the clinic. The investigators hypothesize that, in cancer patients or cancer survivors, the prevalence of the use of psychoactive substances would be higher in the presence of pain, and would be associated with its intensity and its impact on the quality Health-Related Living (HRQoL). The main objective of this study will be to compare, in an adult population of patients suffering from cancer or having had cancer, the prevalence of the consumption of psychoactive substances in painful patients compared to non-painful patients.
Detailed description
Patients will answer to an online questionnaire thanks to associations of cancer patients and social networks, in order to explore their substance use and pain status.
Interventions
BEHAVIORALQuestionnaire (patient reported outcome)
Online self-administered questionnaire exploring substance use, pain, chemotherapy-induced peripheral neuropathy, health-related quality of life, anxiety, depression, social and material deprivation, patients and oncological charactericitcs, and intercurrent pathologies
Sponsors
University Hospital, Clermont-Ferrand
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Adult patient, male or female, declaring himself as suffering or having suffered from cancer and recruited as such via appropriate communication systems (patient associations, etc.)
Exclusion criteria
* Difficulty to understand French language * Residence outside France (will be verified by the information from the department at the start of the questionnaire) * Patient close relative * Protected adults
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| substance use | day 1 | Legal: alcohol, tobacco, electronic cigarette, psychotropic drugs (benzodiazepines, z-drugs, and opioids), CBD, and other susbtances Illegal: cannabis, and other drugs At least once in the past year, at least once in the past month, at least once in the past week, or at least once a day |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Neuropathic pain | day 1 | DN4 interview questionnaire |
| Analgesic use | day 1 | Ongoing analgesic drugs |
| Chemotherapy-induced peripheral neuropathy | day 1 | QLQ-CIPN20 questionnaire |
| Health-related quality of life and symptoms | day 1 | QLQ-C30 questionnaire |
| Pain severity | day 1 | Brief pain inventory |
| Material and social deprivation | day 1 | EPICES questionnaire |
| Sociodemographic characteristics of patient | day 1 | age, sex, height, weight, body mass index, area of residence (urban or rural), socio-professional status (INSEE), and department |
| Oncological characteristic | day 1 | type of cancer, date of cancer diagnosis, and type of treatment (received and/or ongoing) |
| Intercurrent pathologies | day 1 | open question |
| Anxiety and depression | day 1 | HADS questionnaire |
Countries
France
Outcome results
None listed