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Sciatic Nerve Block, Adductor Canal Block, or IPACK Block

Femoral Nerve Block Combined With Sciatic Nerve Block Adductor Canal Block Or (Interspace Between The Popliteal Artery And The Capsule Of The Posterior Knee) IPACK Block For Postoperative Analgesia After Major Knee Surgeries

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05684107
Enrollment
150
Registered
2023-01-13
Start date
2022-11-01
Completion date
2023-12-01
Last updated
2023-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Pain

Keywords

IPACK , Sciatic nerve block , adductor canal block

Brief summary

Comparison between local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) versus adductor canal block (ACB) or sciatic nerve block (anterior approach) in combination with femoral nerve block for postoperative analgesia in major knee surgeries.

Interventions

PROCEDUREIPACK block

the probe is applied to the popliteal fossa for identification of the popliteal artery and femur. Then, the probe is slid distally for revealing the two femoral condyles followed by proximal sliding of the probe until the humps of the femoral condyles disappeared and the flat metaphysis appeared. a spinal needle 22G x 3.5 inches is advanced from the lateral aspect and directed across the space between the popliteal artery and femur and once the needle reached the medial edge of the femur, nearly at the level of the popliteal artery, negative aspiration is confirmed and 20 ml of bupivacaine 0.25% is injected incrementally as the needle was withdrawn

PROCEDUREadductor canal block

the transducer is placed anteromedially, approximately at the junction between the middle and distal third of the thigh or somewhat lower. The saphenous nerve block should be performed at the most distal level where the artery still lies immediately deep to the sartorius muscle, thus minimizing the amount of motor nerve block of the vastus medialis; an adductor canal nerve block is typically performed more proximally, around the mid-thigh level. The needle is inserted in-plane in a lateral-to-medial orientation and advanced toward the femoral artery. Once the needle tip is visualized anterior to the artery and after careful aspiration, 20 ml of bupivacaine 0.25% is injected incrementally as the needle was withdrawn

PROCEDUREsciatic nerve block

patient in a supine position with the hip and knee on the operated side flexed and the leg externally rotated at approximately 45 degrees. The ultrasound transducer is first positioned perpendicular to the skin approximately 8 cm distal to the inguinal crease. The location is then scanned by sliding and tilting the transducer until a clear transverse image of the hyperechoic sciatic nerve located posterior and medial to the lesser trochanter is obtained. a spinal needle 22G x 3.5 inches is advanced parallel and in line with the ultrasound transducer while the sciatic nerve is kept in the middle of the screen. The needle is advanced slowly under real-time ultrasound guidance until it is near the nerve then negative aspiration is confirmed and 20 ml of bupivacaine 0.25% is injected incrementally as the needle was withdrawn

Sponsors

Menoufia University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
40 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* ASA I or II physical status * undergoing elective major knee surgery

Exclusion criteria

* refusal of the patients to give informed consent, * preexisting coagulation disorders, * known allergies to aminoamide local anesthetics, * local infection at the site of the block, * morbid obesity, * hepatic and renal diseases * patients with psychological disorders

Design outcomes

Primary

MeasureTime frameDescription
change of visual analogue scalechange from 0 level every 1 hour for 1st 6 hours,then every 4 hours for next 24 hours and on movementa scale from 0 to 10 as the patient will be asked to express his pain on the scale higher scale means a worse outcome

Secondary

MeasureTime frameDescription
time for fisrt analgesic requestup to 48 hourswhen VAS is 4 or more longer time means a better outcome
total morphine consumptionup to 48 hoursintraoperative and post operative higher consumption means a worse outcome

Countries

Egypt

Contacts

Primary Contactmostafa saieed saieed mansour, MD
mostafa.said@med.menofia.edu.eg01225484055

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026