Chlorhexidine, Hyaluronic Acid, Periodontitis
Conditions
Brief summary
General Objective : To evaluate the outcome of non surgical periodontal therapy with local drug delivery adjunct to scaling and root planning Specific Objective : To determine the effect of intra-pocket application of hyaluronic acid /chlorohexidine gel in non surgical periodontal treatment on clinical periodontal parameters and microbiological level .
Interventions
PROCEDURENon surgical periodontal therapy
Subgingival ultrasonic debridement + manual root planning
Sponsors
University of Sharjah
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Intervention model description
Split mouth RCT
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Age : 20-60 years old * At least 20 remaining teeth * Periodontitis stage III and IV ,Grade A, B and C
Exclusion criteria
* Patients taking specific medications: antibiotic , anticoagulants or anti-inflammatory * Previous periodontal therapy in the past 3-6 months. * Immunocompromised patients * Systemically diseased patients: Diabetes ,osteoporosis etc * History of allergies or hypersensitivity reactions to chlorohexidine or Hyaluronic acid * Pregnant or lactating women. * Heavy Smokers (more than 20/day)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pocket depth | 2 months |
| Bleeding on Probing | 2 months |
| Clinical attachment level | 2 months |
Secondary
| Measure | Time frame |
|---|---|
| Plaque index | 2 months |
Countries
United Arab Emirates
Contacts
Primary ContactProf. Zahi Badran Prof.
Outcome results
None listed