Mottling Score and Central Venous Oxygen Saturation in Septic Shock Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05681052

Enrollment

Registered

2023-01-11

Start date

2022-10-01

Completion date

2023-01-21

Last updated

2023-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Oxygen Saturation, Microcirculation, Mottling Score, Septic Shock

Brief summary

Mottling score and central venous oxygen saturation are described as a clinical evaluation of tissue perfusion. This study describes mottling incidence and mottling score in septic shock patients according to central venous oxygen saturation.

Detailed description

This study prospectively analyzed the data of patients admitted to our ICU between October 2022 to December 2022. All septic patients in whom the ScvO2 was measured and mottling scores were evaluated were included. This study enrolled patients aged ≥ 18 years in septic shock. Those excluded have peripheral arterial disease, black skin, cutaneous infection of the lower limbs, pregnancy, and relative refusal. The characteristics of patients were recorded at admission (H0), including demographics (age, sex, body mass index (BMI), admission the Acute Physiology and Chronic Health Evaluation (APACHE II) score, Glasgow Coma Scale (GCS) and sequential organ failure assessment (SOFA) score. Variables such as plasma lactate level, daily urine output, plasma creatinine level, the ratio of arterial oxygen pressure related to inspired oxygen fraction (PaO2/FiO2), hemoglobin level, heart rate, mean arterial pressure, pulsatile saturation in oxygen (SpO2) and body temperature were recorded at H0 and 6 hours after initial resuscitation (H6).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients aged ≥ 18 years in septic shock.

Exclusion criteria

* patients having the peripheral arterial disease * black skin, * cutaneous infection of the lower limbs * pregnancy * relative refusal

Design outcomes

Primary

Measure	Time frame	Description
Difference in mottling incidence according to ScvO2 level during a septic shock.	at 0th hour, admission; at 6th hour after initial treatment	—
Difference in mottling score according to ScvO2 level during a septic shock.	at 0th hour, admission; at 6th hour after initial treatment	0 score is minimum level, meaning no mottling, meaning better outcome 5 score is maximum level, meaning more mottling, meaning worse outcome

Countries

Turkey (Türkiye)

Contacts

Primary ContactNURCAN KUTLUER KARACA, Asistant Profesor

nurcankutluer@yahoo.com+905386961814

Outcome results