Hematopoietic Stem Cell Transplantation, Cancer
Conditions
Brief summary
To develop and measure the effects of a culturally sensitive yoga program for inpatients
Detailed description
Primary Objective: 1\. To develop a culturally tailored yoga therapy (YT) program for HSCT patients. We will conduct semi-structured interviews with patients from each center to examine cultural norms, culturally sensitive language, and specific factors relevant to yoga and psychosocial support. Secondary Objectives: 1. To optimize the HSCT YT program using an iterative process. Fifteen patients from each center (or until thematic saturation based on exit interviews) will participate in the yoga program two weeks prior to the transplant and throughout the first 30 days of the HSCT. Sessions will be delivered in person, via telehealth (Zoom), or in combination. 2. To examine the feasibility of adherence and follow-up completion. We will declare the intervention feasible if: (a) at least 50% of patients complete a minimum of 50% of the 12 YT sessions, and (b) at least 60% of participants complete follow-up measures at 2 months after transplant (± 7 days).
Interventions
BEHAVIORALYoga Sessions
Participants will have up to 12 sessions, 3 sessions per week starting two weeks before the transplant and throughout the first 30 days of your hospitalization.
BEHAVIORALQuestionnaries
Participants will complete 4 questionnaires about any symptoms you may be having, any anxiety and/or depression you may be having, your quality of life, and your expectations about your treatment.
BEHAVIORALInterviews
Participants will have an exit interview last about 30-45 minutes. The interview will be conducted over the phone or remotely over Zoom, FaceTime, or other approved video call methods.). The interview will be audio and video recorded and transcribed (typed).
Sponsors
M.D. Anderson Cancer Center
National Cancer Institute (NCI)
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Cancer patients scheduled to undergo an autologous or allogeneic HSCT at MD Anderson, HCG, or MNH; 2. Age 18 or older; 3. English, Hindi, or Swahili speaking; 4. Able to sign a written informed consent and be willing to follow protocol requirements.
Exclusion criteria
* Extreme mobility issues that preclude participating in the YT; * Major thought disorders such as schizophrenia or uncontrolled bipolar disorder; * HCT comorbidity score of 3 or higher, excluding cancer diagnoses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient Health Questionnaire-8 (PHQ-8) | through study completion; an average of 1 year | The PHQ-8 is a 8-item self-report questionnaire used to assess bother of depressive symptoms over the past 2 weeks. The PHQ-8 is a 8-item questionnaire to screen for degree of depressive symptoms scored on a 0-24 scale with higher scores indicating greater distress and impairment |
Countries
India, Tanzania, United States
Contacts
CONTACTLorenzo Cohen, PHD
PRINCIPAL_INVESTIGATORLorenzo Cohen, PHD
M.D. Anderson Cancer Center
Outcome results
None listed