Healthy
Conditions
Brief summary
This is a placebo-controlled study conducted to investigates the safety and efficacy of products containing marine collagen peptide and CoQ10 in enhancing skin rejuvenation of Malaysian women. The study duration is 28 days and the skin assessment will be carried out at baseline, Day 14 and Day 28.The main questions it aims to answer are: 1. The effect of product on skin hydration of women in Malaysia. 2. The effect of product on skin elasticity of women in Malaysia. 3. The effect of product on skin wrinkle of women in Malaysia. 4. The skin brightening effect of product on Malaysian women. 5. To observe any adverse effect occurrence with the consumption of the product.
Interventions
OTHERPlacebo
Product doesn't have active ingredients i.e. marine collagen peptide and Coenzyme Q10.
OTHERProduct containing marine collagen peptide and Coenzyme Q10.
Product containing marine collagen peptide and Coenzyme Q10.
Sponsors
Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
35 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Malaysian citizen * Women aged 35 - 45 years old * Willing to participate
Exclusion criteria
* Women with skin diseases or any underlying diseases. * Pregnant, breastfeeding women or planned pregnancy during the study period * Allergy to collagen or other ingredients that may be found in the product. * Women who had any cosmetic procedures such as botox, laser and light treatment, facial surgery, and any procedures that may improve skin hydration, elasticity, wrinkles, and brightening of skin four weeks before the study. * Women who took any dietary supplements, functional foods, or medicines that could have the same or similar effects as the product evaluated in this study in the past three months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in skin hydration from baseline and at Day 14 and Day 28 after consumption of a product. | Baseline, Day 14 and Day 28 | Skin hydration will be assessed using JANUS III skin analyzer and comparison will be made with placebo group. |
| Changes in skin elasticity from baseline and at Day 14 and Day 28 after consumption of a product. | Baseline, Day 14 and Day 28 | Skin elasticity will be assessed using JANUS III skin analyzer comparison will be made with placebo group. |
| Changes in skin wrinkles from baseline and at Day 14 and Day 28 after consumption of a product. | Baseline, Day 14 and Day 28 | Skin wrinkles will be assessed using JANUS III skin analyzer comparison will be made with placebo group. |
| Changes in skin tone from baseline and at Day 14 and Day 28 after consumption of a product. | Baseline, Day 14 and Day 28 | Skin hydration will be assessed using JANUS III skin analyzer comparison will be made with placebo group. |
| Adverse effect after consumption of product containing marine collagen peptide and coenzyme Q10. | 28 Days | Based on adverse effect occurrence on participants that occur during study period (28 days) |
Countries
Malaysia
Outcome results
None listed