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Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss

Relationship Between Habitual Abortion With Thyroid Hormone Values and Anti-TPO (Anti-thyroid Peroxidase Antibody) Positivity

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05680376
Enrollment
103
Registered
2023-01-11
Start date
2018-01-01
Completion date
2022-10-01
Last updated
2023-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autoimmune Thyroiditis, Recurrent Miscarriage

Keywords

Thyroid Hormones, Anti Thyroid Peroxidase Antibody, Recurrent pregnancy loss

Brief summary

The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies. The primary objective is to find out the relationship between recurrent pregnancy loss with thyroid hormone levels and anti-TPO positivity.

Interventions

None listed

Sponsors

Zonguldak Bulent Ecevit University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* women with 2 or more pregnancy loses * for controls women with least one healthy baby

Exclusion criteria

* any other metabolic disease * women with one miscarriage

Design outcomes

Primary

MeasureTime frameDescription
Anti-thyroid Peroxidase Antibodies4 yearspresence of Anti-thyroid Peroxidase Antibodies in both groups
Thyroid Hormone Levels4 yearslevels of Thyroid stimulant Hormone, Thyroxin and triiodothyronine levels

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026