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Lornoxicam Versus Etodolac After Third Molar Surgery

Comparison of Lornoxicam and Etodolac on Edema, Trismus and Pain After Third Molar Surgery

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05679453
Enrollment
20
Registered
2023-01-11
Start date
2022-07-20
Completion date
2022-09-29
Last updated
2023-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edema, Pain, Acute, Trismus

Brief summary

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

Detailed description

20 patients included in study (4 male, 16 female). Lornoxicam and etodolac was given following lower third molar extraction. Pain was evaluated 2., 6., 12., 24., and 48. hours using VAS. Edema was evaluated by measuring tragus-labial commissure, angulus- lateral canthus of eye and angulus mandible-labial commissure. Trismus was evaluated measuring mouth opening by caliper. Edema and Trismus was evaluated by 48. and 168. hours

Interventions

DRUGLornoxicam 8 Mg Oral Tablet

Lornoxicam is a oxicam grup non-steroid antiinflamatuar drug

Sponsors

Kutahya Health Sciences University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Bilateral mesioangular impacted lower third molar * Asymptomatic Third Molar (No history of infection) * Systemically Healthy Person * Person Between aged 18-30

Exclusion criteria

* People who are pregnant and lactation process * People who had any systemic disease * People who are gastrointestinal problems * People who are sensitive to drugs used in study * Lower Third Molar associated with cysts and infections

Design outcomes

Primary

MeasureTime frameDescription
Pain after wisdom tooth extraction2 th hoursPain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)
Edema after wisdom tooth extraction48 th hoursEdema lower third molar removal, Edema was evaluated by using reference line on the face
Trismus after wisdom tooth extraction48 th hours,Trismus lower third molar removal, trismus was evaluated by using caliper

Secondary

MeasureTime frameDescription
Pain after wisdom tooth extraction6 th hoursPain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)
Edema after wisdom tooth extraction168 th hoursEdema lower third molar removal, Edema was evaluated by using reference line on the face
Trismus after wisdom tooth extraction168 th hoursTrismus lower third molar removal, trismus was evaluated by using caliper

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026