Analgesia, Cesarean Section
Conditions
Brief summary
In the current study, the investigators will compare the effects of low-dose intravenous (i.v.) ketamine versus intrathecal Ketamine added to spinal anesthesia on the time to first request for analgesia and maternal pain scores and overall satisfaction in patients undergoing cesarean section.
Interventions
Patients will receive intrathecal Ketamine 0.1mg/kg added to bupivacaine and morphine
Patients will receive IV Ketamine 0.25mg/kg after spinal
Sponsors
Assiut University
Study design
Allocation
NA
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
• Pregnant undergoing elective cesarean section
Exclusion criteria
* Significant coexisting diseases (pregnancy-induced hypertension or diabetes) * body mass index ≥40kg/m2, height \<150cm * Current use of pain medication including opioids * history of substance abuse or hallucinations, cardiovascular disease, diabetes, multiple gestations * chronic pain was excluded. * contraindications to spinal anaesthesia, * severely compromised fetus requiring general anesthesia and those patients who received labor analgesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to the first analgesic request | First Postoperative day |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain scores NRS at rest and on movement; (2, 4, 6, 12, and 24 hours) postoperative | first postoperative day |
Countries
Egypt
Outcome results
None listed