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Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05678608
Enrollment
20
Registered
2023-01-10
Start date
2022-12-13
Completion date
2023-05-31
Last updated
2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cord Tumor

Brief summary

Primary spinal cord tumors constitute 2-4% of all central nervous system neoplasms; they are classfied as extradural, intradural extramedullary (IDEM: 65%), and intramedullary The most commonly seen IDEM tumors are schwannomas, neurofibromas, and meningiomas. \[1\] The less frequently encountered IDEM tumors include ependymomas, lipomas, hemangiomas, metastatic deposits, paragangliomas, nerve sheath myxomas, and vascular tumors.\[2\] Spinal cord tumors can cause different signs and symptoms, especially as tumors grow. The tumors may affect spinal cord or the nerve roots, blood vessels or bones of spine. Signs and symptoms may include: Pain at the site of the tumor due to tumor growth Back pain, often radiating to other parts of body Feeling less sensitive to pain, heat and cold Loss of bowel or bladder function Difficulty walking, muscle weakness . MRI is the investigation of choice,however other investigation such CT or X ray are important to ensure stability of the vertebral column and the optimal management is gross total excision for symptomatic lesions.\[3,4\] Over the years, there has been no significant change in the clinical symptoms and pathology of IDEM tumors. However, there have been dramatic improvements in the diagnosis and treatment with the advances of radiological and surgical techniques. Despite advances in operative techniques and neuroimaging, the morbidity associated with the resection of IDEM tumors continues to be significant \[5,6\]. Here, we examined the surgical outcomes of 20 patients with IDEM spinal cord tumors operated in Neurosurgery department at Sohag university Hospital

Interventions

posterior midline approach and total excision for spinal cord tumors

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients with intradural extramedullary lesion in dorsolumber region

Exclusion criteria

* previous history of spinal surgery * unfit medical patients * multiple level affection * associated cervical lesion * unstable segment

Design outcomes

Primary

MeasureTime frameDescription
american spinal injury association scale6 monthsgrading of impairment for motor and sensory functions grade A for complete sensory and motor loss grade E for normal motor and sensory
visual analogue pain scale6 monthspain scale from zero to ten depend on severity of pain,

Countries

Egypt

Contacts

Primary Contactmohamed M kassem, demonstrator
mohamed011152@med.sohag.edu.eg010980-03153
Backup Contactmohammed M abd el-Aal, professor
01123728094

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026