Benign Prostatic Hyperplasia
Conditions
Keywords
HOLEP, Enucleation, Prostate
Brief summary
Holmium laser enucleation (HOLEP) has became a standard of treatment of large prostates that indicates surgery. HOLEP is widely used nowadays. Many settings are used but no optimal setting was world wide adopted. The aim of this trial is to assess the Low-power Holmium laser enucleation of the prostate (LP-HoLEP)and compare to high-power (HP-HoLEP) for enucleation efficiency pertaining to the advantages of lower cost and minimal postoperative dysuria, storage symptoms, and negative sexual impact.
Interventions
PROCEDUREHOLEP for treating BPH
HoLEP will be performed using 100W Versapulse, Luminis Inc., with 2J/25Hz for LP-HoLEP and 2J/50Hz for HP-HoLEP.
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
double blind
Intervention model description
HoLEP will be performed using 100W Versapulse, Luminis Inc., with 2J/25Hz for LP-HoLEP and 2J/50Hz for HP-HoLEP.
Eligibility
Sex/Gender
MALE
Age
45 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* large prostate indicated for surgical intervention.
Exclusion criteria
* prostate cancer * recurrent adenomas * associated neurologic factors that may affect outcomes (e.g., neurogenic bladder)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Enucleation Efficiency | 3 hours | Enucleated weight/min will be evaluated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dysuria will be assessed by dysuria visual analog scale | 2 weeks | burning micturation after the procedure. Dysuria will be assessed by dysuria visual analog scale |
| The complications of both techniques | 3 months | The complications will be classified according to the modified Clavien classification system. |
Countries
Egypt
Contacts
Primary ContactMohamed F Salman, MD
Outcome results
None listed