Impacted Wisdom Tooth, Pain, Staphylococcus Aureus
Conditions
Keywords
local antibiotic, comparison, platelets rich fibrin
Brief summary
The aim of this study was investigate the effectiveness of Local Antibiotic Applications With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo and In Vitro. The study included a total of 60 patients with impacted mandibular third molar. Patients were evaluated in 3 randomly separated groups. For the first and second group, Platelets Rich Fibrin+ local antibiotics were applied into the tooth socket. For the first group, amoxicillin was applied and for the second group, clindamycin was applied. There was a control group which only Platelets Rich Fibrin was applied into the socket. The outcome variables were pain, swelling, the number of analgesics taken, and trismus. These variables were also assessed based on first, second, third, and seventh days following the operation.
Interventions
DIAGNOSTIC_TESTDiagnosis
All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.
DRUGAnalgesic
Analgesics are prescribed for the patients for all groups.
PROCEDUREtraditional osteotomies
In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).
BIOLOGICALPlatelet Rich Fibrin
Platelet rich fibrin (PRF), is an example and popular procedure for accelerate healing of soft and hard tissue because of the presence of various growth factors.a blood sample was taken without anticoagulant in 10 mL glass-coated plastic tubes that were immediately centrifuged (Elektro-mag M415P) at 3,000 rpm for 10 min (approximately 400 g) (13). The platelet-poor plasma that accumulated at the top of the tubes was discarded.PRF was dissected approximately 2 mm below its contact point with the red corpuscles situated beneath, to include any remaining platelets that may have localized below the junction between the PRF and red corpuscles.
DRUGAntibiotic
no systemic antibiotics are prescribed for the patients for all groups.
Sponsors
Ceren Melahat Donmezer
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* patient with no systemic diseases, no current infection, no smoke, no pregnancy
Exclusion criteria
* no inflammation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| visual analogue scale (VAS) | Day 1 | It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured. |
| swelling | Day 1 | measured using a flexible plastic measuring tape as described by Gabka and Matsumura by measuring the distance from the corner of the mouth to the attachment of the earlobe following the bulge of the cheek and the distance from the outer canthus of the eye to the angle of the mandible. |
| Trismus | Day 1 | Trismus by measuring the distance between the mesial incisal corners of the upper and lower right incisors during maximum mouth opening. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Amount of analgesic tablets | day 1,2,3,7 and 15 | Check the patients analgesic number of days 1,2,3,7 and 15. |
Countries
Cyprus
Outcome results
None listed